Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13372804 | 1.00 | F10 (0.33) | F10HDAC1HDAC2 | |
| SCHEMBL13372859 | 0.92 | F10 (0.34) | F10 | |
| SCHEMBL3309417 | 0.89 | F10 (0.42) | F10 | |
| SCHEMBL3308410 | 0.89 | F10 (0.42) | F10 | |
| SCHEMBL13395130 | 0.89 | F10 (0.42) | F10 | |
| SCHEMBL13372818 | 0.89 | F10 (0.35) | F10HDAC1HDAC2 | |
| SCHEMBL13372902 | 0.87 | F10 (0.39) | F10HDAC1HDAC2 | |
| SCHEMBL13372920 | 0.86 | F10 (0.31) | F10 | |
| SCHEMBL13372870 | 0.85 | F10 (0.33) | F10HDAC1HDAC2 | |
| SCHEMBL13372836 | 0.84 | F10 (0.33) | F10HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132193-B1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2132193-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | Boehringer Ingelheim International GmbH (DE) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008116881-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-02 | — | — | WO | disclosed |