SCHEMBL44337

SCHEMBL44337

Clc1cn[nH]c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1385812 0.69 AKT2 (0.67)
SCHEMBL277590 0.69
SCHEMBL3740850 0.67 AKT2 (0.70)
Hydrochloric Acid SCHEMBL17713738 0.67
SCHEMBL31135323 0.65 CYP19A1 (0.49)
Hydrochloric Acid SCHEMBL28973063 0.65 AKT2 (0.67)
SCHEMBL954980 0.65
SCHEMBL5928979 0.62
Hydrochloric Acid SCHEMBL4562672 0.62
Fomepizole SCHEMBL20769777 0.62 KCNH2 (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036614-A Pyrazolyl cyclo trinuclear complex, synthesis method thereof and application thereof in X-ray imaging field 中山大学 2026-05-15 CN claimed
WO-2025224076-A1 SUBSTITUTED ARYLPYRAZINES AND SALTS THEREOF, AND USE THEREOF AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2025-10-30 WO claimed
WO-2025132542-A1 MACROCYCLIC OREXIN AGONISTS IDORSIA PHARMACEUTICALS LTD (CH) 2025-06-26 WO claimed
CN-117964636-B Triazolopyrimidines method for synthesizing compound 上海陶术生物科技股份有限公司 2025-03-21 CN claimed
CN-118546179-A Preparation method of pyrazole trinuclear cobalt-based catalyst 安徽大学 2024-08-27 CN claimed
CN-118324697-A High-energy low-inductance eutectic compound based on 3,4, 5-trinitropyrazole and preparation method thereof 常州千沐新能源有限公司 2024-07-12 CN claimed
US-20240228912-A9 COMPOSITION FOR CLEANING SEMICONDUCTOR SUBSTRATE, AND CLEANING METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-07-11 US claimed
CN-118063400-A High-energy insensitive eutectic compound 5AT-ADNP and preparation method thereof 常州千沐新能源有限公司 2024-05-24 CN claimed
CN-118026934-A N-azole-4-methylbenzenesulfonamide compound and preparation method and application thereof 安徽理工大学 2024-05-14 CN claimed
CN-117964636-A Synthesis method of triazolopyrimidine compound 上海陶术生物科技有限公司 2024-05-03 CN claimed
EP-0973767-A1 INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS Dupont Pharmaceuticals Company (US) 2000-01-26 EP claimed
EP-0624585-B1 Process for the preparation of 2-(4-(4-(4-chloro-1-pyrazolyl)butyl)1-piperazinyl)pyrimidine ESTEVE LABOR DR (ES) 1999-08-18 EP claimed
WO-1998043969-A1 INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS DUPONT PHARMACEUTICALS COMPANY (US) 1998-10-08 WO claimed
US-5536836-A Process for the preparation of 2-(4-[4-(4-chloro-1-pyrazolyl)butyl]-1-piperazinyl)pyrimidine (Lesopitron) LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1996-07-16 US claimed
CN-1100096-A Process for the preparation of 2-{4-[4(4-chloro-1-pyrazolyl)butyl]1-piperazinyl} pyrimidine (lesopitron) ENRIQUE MANOSAS BARRERA ATTORN (ES) 1995-03-15 CN claimed
EP-0624585-A1 Process for the preparation of 2-(4-(4-(4-chloro-1-pyrazolyl)butyl)1-piperazinyl)pyrimidine LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1994-11-17 EP claimed
EP-0371361-B1 Process for the preparation of 4-chlorpyrazoles BASF AG (DE) 1994-03-02 EP claimed
US-5047551-A Preparation of 4-chloropyrazoles BASF AKTIENGESELLSCHAFT (DE) 1991-09-10 US claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed
US-4321395-A Preparation of acetanilides BASF AKTIENGESELLSCHAFT (DE) 1982-03-23 US claimed