Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 17/20 | 0.58 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3212010 | 0.90 | PTGER1 (0.60) | PTGER1USP30 | |
| SCHEMBL3215714 | 0.88 | PTGER1 (0.70) | PTGER1USP30 | |
| SCHEMBL3220347 | 0.87 | PTGER1 (0.68) | PTGER1USP30 | |
| SCHEMBL4428672 | 0.85 | PTGER1 (0.65) | PTGER1 | |
| SCHEMBL13424487 | 0.85 | PTGER1 (0.80) | PTGER1USP30 | |
| Hydrochloric Acid SCHEMBL3216771 | 0.84 | PTGER1 (0.78) | PTGER1USP30 | |
| SCHEMBL3220965 | 0.83 | PTGER1 (0.63) | PTGER1 | |
| SCHEMBL4431811 | 0.82 | PTGER1 (0.62) | PTGER1 | |
| SCHEMBL3214559 | 0.82 | PTGER1 (0.78) | PTGER1 | |
| SCHEMBL3203681 | 0.82 | PTGER1 (0.77) | PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129670-A2 | BENZOFURAN COMPOUNDS USEFUL IN THE TREATMENT OF CONDITIONS MEDIATED BY THE ACTION OF PGE2 AT THE EP1 RECEPTOR | Glaxo Group Limited (GB) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008098978-A2 | BENZOFURAN COMPOUNDS USEFUL IN THE TREATMENT OF CONDITIONS MEDIATED BY THE ACTION OF PGE2 AT THE EP1 RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-08-21 | — | — | WO | disclosed |