Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.50 |
| ▸ | GBA2 | Q9HCG7 | 14/20 | 0.47 |
| ▸ | GBA1 | P04062 | 4/20 | 0.47 |
| ▸ | UGCG | Q16739 | 3/20 | 0.47 |
| ▸ | MGAM | O43451 | 3/20 | 0.47 |
| ▸ | SI | P14410 | 2/20 | 0.47 |
| ▸ | AGL | P35573 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790138 | 0.87 | GAA (0.53) | GAAGBA2GBA1UGCGMGAM | |
| SCHEMBL466539 | 0.84 | GBA2 (0.55) | GAAGBA2GBA1UGCGMGAM | |
| SCHEMBL3021725 | 0.81 | GAA (0.56) | GAAGBA2GBA1UGCGMGAM | |
| SCHEMBL3017615 | 0.76 | GBA2 (0.56) | GAAGBA2GBA1UGCGMGAM | |
| SCHEMBL14319851 | 0.73 | GBA2 (0.59) | GAAGBA2GBA1UGCGMGAM | |
| SCHEMBL6134836 | 0.71 | AGL (0.48) | GAAGBA2GBA1UGCGMGAM | |
| SCHEMBL12589798 | 0.71 | GAA (0.50) | GAAGBA2GBA1UGCGMGAM | |
| SCHEMBL6135767 | 0.71 | AGL (0.48) | GAAGBA2GBA1UGCGMGAM | |
| SCHEMBL6135319 | 0.71 | AGL (0.48) | GAAGBA2GBA1UGCGMGAM | |
| SCHEMBL2787976 | 0.71 | GAA (0.63) | GAAGBA2GBA1UGCGMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049126-A2 | LIPOSOME TREATMENT OF VIRAL INFECTIONS | United Therapeutics Corporation (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008088581-A2 | LIPOSOME TREATMENT OF VIRAL INFECTIONS | UNITED THERAPEUTICS CORPORATION (US) | 2008-07-24 | — | — | WO | disclosed |