Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31685548 | 0.71 | MEN1 (0.36) | MEN1BLMKMT2AATAD2ADORA2A | |
| SCHEMBL19472376 | 0.71 | MEN1 (0.36) | MEN1BLMKMT2AATAD2ADORA2A | |
| SCHEMBL17356112 | 0.70 | GDA (0.36) | MEN1BLMKMT2AATAD2ATIC | |
| SCHEMBL18545322 | 0.70 | GDA (0.43) | MEN1BLMKMT2AATAD2BRD4 | |
| SCHEMBL31685265 | 0.69 | MEN1 (0.34) | MEN1BLMKMT2AADORA2AADORA2B | |
| SCHEMBL31685445 | 0.69 | MEN1 (0.34) | MEN1BLMKMT2A | |
| SCHEMBL6674432 | 0.66 | GDA (0.38) | MEN1BLMKMT2AATAD2ADORA2A | |
| SCHEMBL21527478 | 0.63 | PDE4A (0.37) | MEN1BLMKMT2APDE4APDE4B | |
| SCHEMBL2142794 | 0.63 | MEN1 (0.34) | MEN1BLMKMT2AATAD2ADORA2A | |
| SCHEMBL31685332 | 0.63 | MEN1 (0.34) | MEN1BLMKMT2AATAD2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158719-A2 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | HYDRA BIOSCIENCES, INC. (US) | 2009-12-30 | — | — | WO | disclosed |