Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 6/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | VHL | P40337 | 4/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NRP1 | O14786 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434683 | 1.00 | ATM (0.44) | ATMNAALAD2FOLH1VHLPRSS1 | |
| SCHEMBL29391935 | 0.90 | NAALAD2 (0.42) | ATMNAALAD2FOLH1VHLPRSS1 | |
| SCHEMBL29721137 | 0.89 | NAALAD2 (0.39) | NAALAD2FOLH1VHLPRSS1TPSAB1 | |
| SCHEMBL29390679 | 0.87 | NAALAD2 (0.39) | NAALAD2FOLH1VHLSMN1; SMN2 | |
| SCHEMBL4440604 | 0.83 | ATM (0.50) | ATMNAALAD2FOLH1VHLPRSS1 | |
| SCHEMBL4440608 | 0.83 | ATM (0.50) | ATMNAALAD2FOLH1VHLPRSS1 | |
| SCHEMBL31110301 | 0.82 | F2 (0.47) | NAALAD2FOLH1VHLF2SMN1; SMN2 | |
| SCHEMBL21711187 | 0.82 | F2 (0.47) | NAALAD2FOLH1VHLF2SMN1; SMN2 | |
| SCHEMBL4432404 | 0.81 | ATM (0.50) | ATMVHLPRSS1TPSAB1F2 | |
| SCHEMBL4432403 | 0.81 | ATM (0.50) | ATMVHLPRSS1TPSAB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2117536-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | Beiersdorf AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008101693-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | BEIERSDORF AG (DE) | 2008-08-28 | — | — | WO | disclosed |