⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5554 | 0.96 | — | — | |
| SCHEMBL771708 | 0.96 | HRH3 (0.45) | — | |
| SCHEMBL692325 | 0.96 | HRH3 (0.45) | — | |
| SCHEMBL737460 | 0.96 | — | — | |
| SCHEMBL645664 | 0.92 | — | — | |
| SCHEMBL3062588 | 0.87 | HRH3 (0.46) | — | |
| SCHEMBL23772 | 0.84 | — | — | |
| SCHEMBL771417 | 0.76 | KMT2A (0.39) | — | |
| SCHEMBL772297 | 0.74 | — | — | |
| SCHEMBL771676 | 0.74 | CHKA (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6920 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029739-B2 | SHP2 inhibitor and use thereof | KANAPH THERAPEUTICS INC. (KR) | 2024-07-09 | — | — | US | claimed |
| CN-115611856-B | Piperidine derivative and pharmaceutical composition, preparation method and application thereof | 宜昌人福药业有限责任公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118184614-A | Substituted benzo five-membered unsaturated heterocyclic compounds, and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-06-14 | — | — | CN | claimed |
| US-20240189306-A1 | SHP2 INHIBITOR AND USE THEREOF | KANAPH THERAPEUTICS INC. (KR) | 2024-06-13 | — | — | US | claimed |
| WO-2024120454-A1 | BIS-PHOSPHATIDYL AMINE COMPOUNDS CONTAINING MULTIPLE TERTIARY AMINO STRUCTURES, AND COMPOSITION AND USE THEREOF | 北京大学 | 2024-06-13 | — | — | WO | claimed |
| CN-112437773-B | Catechol derivatives or salts thereof, process for preparing the same and pharmaceutical compositions containing the same | 六合医药科技有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-118146262-A | Bi-phosphatidyl amide compound containing multiple tertiary amino structures, composition and application thereof | 北京大学 | 2024-06-07 | — | — | CN | claimed |
| CN-118159542-A | Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents | 拜耳公司 | 2024-06-07 | — | — | CN | claimed |
| CN-118084864-A | PRMT4 inhibitor, and pharmaceutical composition, pharmaceutical preparation and application thereof | 北京福元医药股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| WO-2024104425-A1 | KRAS INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 广东东阳光药业股份有限公司 | 2024-05-23 | — | — | WO | claimed |
| US-4129733-A | HERBICIDE | THE DOW CHEMICAL COMPANY (US) | 1978-12-12 | — | — | US | claimed |
| US-4104380-A | Dibenzyl glycolic acid derivatives | WARNER-LAMBERT COMPANY (US) | 1978-08-01 | — | — | US | claimed |
| US-4093805-A | ANTIDEPRESSANT AND ANTIANXIETY ACTIVITY | THE DOW CHEMICAL COMPANY (US) | 1978-06-06 | — | — | US | claimed |
| US-4085278-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1978-04-18 | — | — | US | claimed |
| US-4085279-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1978-04-18 | — | — | US | claimed |
| US-4076937-A | Dibenzyl glycolic acid derivatives | WARNER-LAMBERT COMPANY (US) | 1978-02-28 | — | — | US | claimed |
| US-3989507-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1976-11-02 | — | — | US | claimed |
| US-3959270-A | DIURETICS, ANTIHYPERTENSIVE, ANTIULCER, ANTIINFLAMMATORY, SEDATIVES, ANALGESICS | DELALANDE S.A. (FR) | 1976-05-25 | — | — | US | claimed |
| US-3956294-A | AZO DYES, PESTICIDES, ANALEPTICS, ANALGESICS, DIURETICS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | claimed |
| US-3933800-A | O-SUBSTITUTED OXIMES, MICROBIOCIDES | GRUPPO LEPETIT S.P.A. (IT) | 1976-01-20 | — | — | US | claimed |