Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4137650 | 0.94 | TRPV1 (0.66) | TRPV1 | |
| SCHEMBL4431113 | 0.93 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL4141271 | 0.91 | TRPV1 (0.62) | TRPV1 | |
| SCHEMBL4146443 | 0.89 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL4138375 | 0.87 | TRPV1 (0.72) | TRPV1 | |
| SCHEMBL4137104 | 0.87 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL15875914 | 0.86 | TRPV1 (0.63) | TRPV1 | |
| SCHEMBL4140890 | 0.83 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL4435553 | 0.83 | TRPV1 (0.44) | TRPV1 | |
| SCHEMBL4140635 | 0.82 | TRPV1 (0.71) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137178-A2 | NOVEL VANILLOID RECEPTOR LIGANDS AND THE USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008125342-A2 | NOVEL VANILLOID RECEPTOR LIGANDS AND THE USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2008-10-23 | — | — | WO | disclosed |