Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 18/20 | 0.52 |
| ▸ | PRKCA | P17252 | 3/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965901 | 0.75 | PRKCQ (0.61) | PRKCQPRKCAPRKCD | |
| SCHEMBL9009726 | 0.74 | PRKCQ (0.55) | PRKCQPRKCAPRKCD | |
| SCHEMBL8966905 | 0.72 | PRKCQ (0.58) | PRKCQPRKCAPRKCD | |
| SCHEMBL11996535 | 0.69 | PRKCQ (0.43) | PRKCQPRKCAPRKCD | |
| SCHEMBL8965171 | 0.69 | PRKCQ (1.00) | PRKCQPRKCAPRKCD | |
| SCHEMBL8965220 | 0.68 | PRKCQ (0.52) | PRKCQPRKCAPRKCD | |
| SCHEMBL8965885 | 0.67 | PRKCQ (0.75) | PRKCQPRKCAPRKCD | |
| SCHEMBL8965501 | 0.67 | PRKCQ (0.75) | PRKCQPRKCAPRKCD | |
| SCHEMBL17506337 | 0.67 | NAPRT (0.41) | PRKCQPRKCAPRKCDSLC6A2SLC6A4 | |
| SCHEMBL1479523 | 0.67 | HRH3 (0.58) | PRKCQPRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121613-A2 | 2-AMINOPYRIDINE DERIVATIVES USEFUL AS KINASE INHIBITORS | Vertex Pharmaceuticals, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008094992-A2 | 2-AMINOPYRIDINE DERIVATIVES USEFUL AS KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-08-07 | — | — | WO | disclosed |