⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330603 | 0.77 | — | — | |
| SCHEMBL7796924 | 0.77 | — | — | |
| SCHEMBL4326330 | 0.77 | — | — | |
| SCHEMBL14469982 | 0.77 | — | — | |
| SCHEMBL14535150 | 0.77 | — | — | |
| SCHEMBL24025862 | 0.77 | PDE4D (0.31) | — | |
| SCHEMBL18912897 | 0.77 | — | — | |
| SCHEMBL13594472 | 0.77 | — | — | |
| SCHEMBL13914151 | 0.77 | — | — | |
| SCHEMBL4984741 | 0.77 | PDE4D (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561080-A | anti-GAL 3 antibody formulations and methods of use thereof | 真和制药有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-116157151-A | Methods of treating inflammatory diseases by blocking galectin-3 | 真和制药有限公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-2021506-A2 | USE OF PRODUCTS OF PCR AMPLIFICATION CARRYING ELEMENTS OF SECONDARY STRUCTURE TO IMPROVE PCR-BASED NUCLEIC ACID DETECTION | Kutyavin, Igor (US) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007127999-A2 | USE OF PRODUCTS OF PCR AMPLIFICATION CARRYING ELEMENTS OF SECONDARY STRUCTURE TO IMPROVE PCR-BASED NUCLEIC ACID DETECTION | KUTYAVIN IGOR (US) | 2007-11-08 | — | — | WO | disclosed |
| WO-1999024621-A9 | METHODS AND COMPOSITIONS FOR DETECTION OF SPECIFIC NUCLEOTIDE SEQUENCES | CYGENE INC (US) | 2001-05-31 | — | — | WO | disclosed |
| EP-1030936-A2 | METHODS AND COMPOSITIONS FOR DETECTION OF SPECIFIC NUCLEOTIDE SEQUENCES | Cygene, Inc. (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024621-A2 | METHODS AND COMPOSITIONS FOR DETECTION OF SPECIFIC NUCLEOTIDE SEQUENCES | CYGENE, INC. (US) | 1999-05-20 | — | — | WO | disclosed |
| US-5808038-A | ANTICARCER AGENT | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-09-15 | — | — | US | disclosed |
| US-5548076-A | CONDENSING A BLOCKED NUCLEOSIDE BOUND TO A CARRIER | GENENTECH, INC. (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0219342-B1 | Method and reagents for in vitro oligonucleotide synthesis | GENENTECH INC (US) | 1994-03-16 | — | — | EP | disclosed |
| US-5264566-A | Method for in vitro oligonucleotide synthesis using H-phosphonates | GENENTECH, INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4959463-A | Intermediates | GENENTECH, INC. (US) | 1990-09-25 | — | — | US | disclosed |
| WO-1989009780-A1 | SITE-SPECIFIC TRITIUM-LABELED OLIGODEOXYNUCLEOTIDES | CHEMICAL INDUSTRY INSTITUTE OF TOXICOLOGY (US) | 1989-10-19 | — | — | WO | disclosed |
| EP-0219342-A2 | Method and reagents for in vitro oligonucleotide synthesis | GENENTECH, INC. (US) | 1987-04-22 | — | — | EP | disclosed |