Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 15/20 | 0.52 |
| ▸ | CNR2 | P34972 | 5/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27609617 | 0.88 | CNR1 (0.65) | PTGS2CNR1CNR2KMT2A | |
| SCHEMBL6335073 | 0.87 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL27759611 | 0.86 | CNR1 (0.55) | PTGS2CNR1CNR2 | |
| SCHEMBL3592562 | 0.85 | CNR1 (0.53) | PTGS2CNR1CNR2KMT2AMEN1 | |
| SCHEMBL5080838 | 0.81 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL3679902 | 0.81 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL28750916 | 0.81 | CNR1 (0.58) | PTGS2CNR1CNR2RXRANR1H2 | |
| Hydrochloric Acid SCHEMBL6334805 | 0.80 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL6334708 | 0.80 | CNR1 (0.52) | CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL6614269 | 0.80 | CNR1 (0.57) | PTGS2CNR1CNR2RXRANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101431994-A | Use of CBx cannabinoid receptor modulators as potassium channel modulators | SOLVAY PHARM GMBH (DE) | 2009-05-13 | — | — | CN | claimed |
| CN-101431998-A | Containing CBxPharmaceutical compositions of cannabinoid receptor modulators and potassium channel modulators | SOLVAY PHARM GMBH (DE) | 2009-05-13 | — | — | CN | claimed |
| CN-101431998-A | Containing CBxPharmaceutical compositions of cannabinoid receptor modulators and potassium channel modulators | SOLVAY PHARM GMBH (DE) | 2009-05-13 | — | — | CN | disclosed |
| CN-101431994-A | Use of CBx cannabinoid receptor modulators as potassium channel modulators | SOLVAY PHARM GMBH (DE) | 2009-05-13 | — | — | CN | disclosed |
| EP-2026798-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS | Solvay Pharmaceuticals GmbH (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007125048-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-11-08 | — | — | WO | disclosed |