Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1051565 | 1.00 | LPAR3 (0.50) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL11536052 | 1.00 | LPAR3 (0.50) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL5453958 | 1.00 | LPAR3 (0.50) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL10626501 | 1.00 | LPAR3 (0.50) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL8467826 | 1.00 | LPAR3 (0.50) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL1045692 | 1.00 | LPAR3 (0.50) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL8469249 | 1.00 | LPAR3 (0.50) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL1050586 | 1.00 | LPAR3 (0.50) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL8467690 | 1.00 | LPAR3 (0.50) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL1047247 | 1.00 | LPAR3 (0.50) | LPAR3LPAR2LPAR1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2126014-B1 | LUBRICATING OIL COMPOSITION COMPRISING AN EPOXIDISED ESTER AND AN ASPARTIC ACID DERIVATIVE | SHELL INT RESEARCH (NL) | 2012-08-29 | — | — | EP | disclosed |
| EP-2126014-A1 | LUBRICATING OIL COMPOSITION COMPRISING AN EPOXIDISED ESTER AND AN ASPARTIC ACID DERIVATIVE | Shell Internationale Research Maatschappij B.V. (NL) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008074760-A1 | LUBRICATING OIL COMPOSITION COMPRISING AN EPOXIDISED ESTER AND AN ASPARTIC ACID DERIVATIVE | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2008-06-26 | — | — | WO | disclosed |