Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771912 | 0.83 | — | — | |
| SCHEMBL16103942 | 0.82 | SLC6A2 (0.43) | SLC6A4SLC6A2SLC6A3NOS3NOS1 | |
| SCHEMBL11441151 | 0.82 | SLC6A2 (0.43) | SLC6A4SLC6A2SLC6A3NOS3NOS1 | |
| SCHEMBL26197502 | 0.82 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3NOS3NOS1 | |
| SCHEMBL12120285 | 0.82 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3NOS3NOS1 | |
| SCHEMBL12120515 | 0.80 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3NOS3NOS1 | |
| SCHEMBL6111793 | 0.80 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3NOS3NOS1 | |
| Bromide SCHEMBL1307607 | 0.80 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3NOS3NOS1 | |
| SCHEMBL10761665 | 0.80 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3NOS3NOS1 | |
| SCHEMBL19292100 | 0.78 | SLC6A2 (0.45) | SLC6A4SLC6A2SLC6A3NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137187-A1 | PYRAZOLO [1,5-A]PYRIMIDINES AS INHIBITORS OF STEAROYL-COA DESATURASE | Inovacia AB (SE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008116898-A1 | PYRAZOLO [1,5-A]PYRIMIDINES AS INHIBITORS OF STEAROYL-COA DESATURASE | BIOVITRUM AB (PUBL) (SE) | 2008-10-02 | — | — | WO | disclosed |