Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.80 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563295 | 0.98 | TSHR (0.83) | TSHRNAAAPOLBAPEX1HTT | |
| SCHEMBL10594310 | 0.98 | TSHR (0.83) | TSHRNAAAPOLBAPEX1HTT | |
| SCHEMBL11355647 | 0.94 | TSHR (0.75) | TSHRNAAAPOLBAPEX1HTT | |
| SCHEMBL18823247 | 0.93 | TSHR (0.72) | TSHRNAAAPOLBAPEX1HTT | |
| SCHEMBL18823426 | 0.93 | TSHR (0.72) | TSHRNAAAPOLBAPEX1HTT | |
| SCHEMBL18822940 | 0.93 | TSHR (0.72) | TSHRNAAAPOLBAPEX1HTT | |
| SCHEMBL18823318 | 0.93 | TSHR (0.72) | TSHRNAAAPOLBAPEX1HTT | |
| SCHEMBL9320768 | 0.92 | TSHR (0.73) | TSHRNAAAPOLBAPEX1HTT | |
| SCHEMBL9321668 | 0.92 | TSHR (0.73) | TSHRNAAAPOLBAPEX1HTT | |
| SCHEMBL11850141 | 0.91 | TSHR (0.70) | TSHRNAAAALDH1A1RAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124817-A2 | BIOABSORBABLE COATINGS FOR MEDICAL DEVICES | ICON Medical Corp. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008112458-A2 | BIOABSORBABLE COATINGS FOR MEDICAL DEVICES | ICON MEDICAL CORP (US) | 2008-09-18 | — | — | WO | disclosed |
| US-4327011-A | Printing ink and vehicle therefor | CENTURY INKS CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |