⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437233 | 1.00 | — | — | |
| SCHEMBL21516128 | 0.62 | — | — | |
| SCHEMBL3395164 | 0.61 | — | — | |
| SCHEMBL3395160 | 0.61 | — | — | |
| Iodide SCHEMBL16961520 | 0.58 | — | — | |
| SCHEMBL17165161 | 0.56 | — | — | |
| SCHEMBL18640778 | 0.56 | — | — | |
| SCHEMBL40602 | 0.56 | — | — | |
| SCHEMBL2143481 | 0.56 | — | — | |
| SCHEMBL2691891 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626239-B1 | EZH2 INHIBITOR COMBINED WITH BTK INHIBITOR FOR TREATING TUMOR | JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN) | 2024-07-03 | — | — | EP | disclosed |
| WO-2024131843-A1 | ANTIBODY-DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 苏州宜联生物医药有限公司 | 2024-06-27 | — | — | WO | disclosed |
| CN-115703760-B | 2, 4-Disubstituted pyrimidine cyclin dependent kinase enzyme inhibitor and preparation method and application thereof | 山东大学 | 2024-05-31 | — | — | CN | disclosed |
| EP-3636628-B1 | 13-OXIDIZED INGENOL DERIVATIVE AND USE THEREOF | TIANJIN PHARMACEUTICAL DA REN TANG GROUP CORP LTD TRADITIONAL CHINESE MEDICINE RES INSTITUTE (CN) | 2024-05-29 | — | — | EP | disclosed |
| CN-118005630-A | ZAK inhibitor, preparation method and application thereof | 中国科学院上海营养与健康研究所 | 2024-05-10 | — | — | CN | disclosed |
| WO-2024093956-A1 | POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR | 山东轩竹医药科技有限公司 | 2024-05-10 | — | — | WO | disclosed |
| US-11970506-B2 | Bioactive molecule conjugate, preparation method and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2024-04-30 | — | — | US | disclosed |
| WO-2024067754-A1 | AURISTATIN DRUG WITH HIGH-STABILITY HYDROPHILIC LINKING UNIT AND CONJUGATE THEREOF | 成都百利多特生物药业有限责任公司 | 2024-04-04 | — | — | WO | disclosed |
| US-20240108745-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | MEDILINK THERAPEUTICS (SUZHOU) CO., LTD. (CN) | 2024-04-04 | — | — | US | disclosed |
| WO-2024055879-A1 | CLASS OF FUSED BICYCLIC COMPOUNDS, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2024-03-21 | — | — | WO | disclosed |
| EP-2781520-A1 | THREE-RING PI3K AND/OR MTOR INHIBITOR | Xuanzhu Pharma Co., Ltd. (CN) | 2014-09-24 | — | — | EP | disclosed |
| EP-2781508-A1 | NITROGEN-CONTAINING FUSED RING COMPOUNDS FOR USE AS CRTH2 ANTAGONISTS | KBP Biosciences Co., Ltd. (CN) | 2014-09-24 | — | — | EP | disclosed |
| US-20140243288-A1 | FUSED RING-CONTAINING OXAZOLIDINONES ANTIBIOTICS | Xuanzhu Pharma Co., Ltd. (CN) | 2014-08-28 | — | — | US | disclosed |
| EP-2762480-A1 | OXAZOLIDINONE ANTIBIOTICS CONTAINING FUSED RING | Xuanzhu Pharma Co., Ltd. (CN) | 2014-08-06 | — | — | EP | disclosed |
| US-20140179638-A1 | 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS | KBP BIOSCIENCES CO., LTD. (CN) | 2014-06-26 | — | — | US | disclosed |
| EP-2738156-A1 | 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUND | KBP Biosciences Co., Ltd. (CN) | 2014-06-04 | — | — | EP | disclosed |
| US-8071600-B2 | Derivatives of 4-piperazin-1-yl-4-benzo[B]thiophene suitable for the treatment of CNS disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-12-06 | — | — | US | disclosed |
| US-20090264404-A1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-10-22 | — | — | US | disclosed |
| CN-1356913-A | vitronectin receptor antagonist drugs | DU PONT PHARM CO (US) | 2002-07-03 | — | — | CN | disclosed |
| US-5066576-A | Yellow coupler with good photostability | FUJI PHOTO FILM CO., LTD. (JP) | 1991-11-19 | — | — | US | disclosed |