Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.31 |
| ▸ | OTC | P00480 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428219 | 1.00 | PLG (0.41) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL4426832 | 1.00 | PLG (0.41) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL4438412 | 0.97 | PLG (0.40) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL29401470 | 0.91 | PLG (0.37) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL15406855 | 0.91 | PLG (0.37) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL21690009 | 0.91 | PLG (0.37) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL20561401 | 0.91 | PLG (0.37) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL18586526 | 0.91 | PLG (0.39) | PLGPLAUF10KLKB1F2 | |
| Hydrochloric Acid SCHEMBL16893616 | 0.90 | PLG (0.37) | PLGPLAUF10KLKB1F2 | |
| Hydrochloric Acid SCHEMBL4994024 | 0.90 | PLG (0.37) | PLGPLAUF10KLKB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524261-B1 | EXENDIN FOR USE IN TREATING DIABETES AND REDUCING BODY WEIGHT | AMYLIN PHARMACEUTICALS LLC (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2019115609-A1 | SACCHARIDE FUNCTIONALISED CARBABORANE CONJUGATES OF HUMAN PEPTIDE Y | UNIVERSITÄT LEIPZIG (DE) | 2019-06-20 | — | — | WO | disclosed |
| EP-2125739-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2009-12-02 | — | — | EP | disclosed |
| US-7541430-B2 | Peptides for use in treating obesity | NOVO NORDISK A/S (DK) | 2009-06-02 | — | — | US | disclosed |
| US-7541430-B2 | Peptides for use in treating obesity | NOVO NORDISK A/S (DK) | 2009-06-02 | — | — | US | disclosed |
| US-20090088388-A1 | Peptides for Use In Treating Obesity | NOVO NORDISK A/S (DK) | 2009-04-02 | — | — | US | disclosed |
| US-20090088388-A1 | Peptides for Use In Treating Obesity | NOVO NORDISK A/S (DK) | 2009-04-02 | — | — | US | disclosed |
| US-20080207493-A1 | Compounds for Use in the Treatment of Obesity | NOVO NORDISK A/S (DK) | 2008-08-28 | — | — | US | disclosed |
| US-20080200366-A1 | Trimeric Peptides for Use in Treating Obesity | NOVO NORDISK A/S (DK) | 2008-08-21 | — | — | US | disclosed |
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
| WO-2008079371-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |
| US-20070244054-A1 | Peptides for use in treating obesity | NOVO NORDISK A/S (DK) | 2007-10-18 | — | — | US | disclosed |
| US-20070244054-A1 | Peptides for use in treating obesity | NOVO NORDISK A/S (DK) | 2007-10-18 | — | — | US | disclosed |
| WO-2007068718-A1 | POLYPEPTIDE PROTRACTING TAGS | NOVO NORDISK A/S (DK) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200366-A1 | Trimeric Peptides for Use in Treating Obesity | MC4R, GIPR, MC3R | PLG 880/4885PLAU 1078/4885F10 1901/4885 |
| US-20070244054-A1 | Peptides for use in treating obesity | NPY4R, GLP1R, NPY1R | PLG 1986/4885PLAU 399/4885F10 192/4885 |
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | C3AR1, C5, C5AR1 | PLG 52/4885PLAU 156/4885F10 432/4885 |
| US-20080207493-A1 | Compounds for Use in the Treatment of Obesity | MC4R, MC5R, MC3R | PLG 591/4885PLAU 497/4885F10 1991/4885 |
| US-20090088388-A1 | Peptides for Use In Treating Obesity | NPY4R, GLP1R, NPY1R | PLG 1986/4885PLAU 399/4885F10 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.