Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1837809 | 1.00 | TAAR1 (0.78) | TAAR1 | |
| SCHEMBL1837806 | 1.00 | TAAR1 (0.78) | TAAR1 | |
| SCHEMBL3616189 | 0.88 | TAAR1 (1.00) | TAAR1 | |
| SCHEMBL3616186 | 0.88 | TAAR1 (1.00) | TAAR1 | |
| SCHEMBL1833346 | 0.81 | TAAR1 (0.75) | TAAR1 | |
| SCHEMBL1833340 | 0.81 | TAAR1 (0.75) | TAAR1 | |
| SCHEMBL3617280 | 0.81 | TAAR1 (1.00) | TAAR1 | |
| SCHEMBL3617283 | 0.81 | TAAR1 (1.00) | TAAR1 | |
| SCHEMBL3617830 | 0.81 | TAAR1 (1.00) | TAAR1 | |
| SCHEMBL3612359 | 0.79 | TAAR1 (1.00) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114906-A1 | NOVEL 2-AMINOOXAZOLINES AS TAAR1 LIGANDS FOR CNS DISORDERS | F. Hoffmann-Roche AG (CH) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008092785-A1 | NOVEL 2-AMINOOXAZOLINES AS TAAR1 LIGANDS FOR CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-08-07 | — | — | WO | disclosed |