Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | STK17A | Q9UEE5 | 7/20 | 0.49 |
| ▸ | STK17B | O94768 | 5/20 | 0.49 |
| ▸ | TNK2 | Q07912 | 6/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | ROS1 | P08922 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3149943 | 0.99 | SYK (0.54) | SYKBRD4STK17ASTK17BTNK2 | |
| SCHEMBL3814175 | 0.81 | SYK (0.56) | SYKBRD4ALKLRRK2 | |
| SCHEMBL24258127 | 0.79 | TNK2 (0.55) | STK17ASTK17BTNK2CHEK1JAK2 | |
| SCHEMBL21485123 | 0.78 | IGF1R (0.49) | STK17ASTK17BTNK2CHEK1JAK2 | |
| SCHEMBL26361454 | 0.76 | TNK2 (0.54) | SYKSTK17ASTK17BTNK2CHEK1 | |
| SCHEMBL24258144 | 0.74 | IRAK1 (0.49) | BRD4TNK2CHEK1JAK2ABL1 | |
| SCHEMBL18488173 | 0.74 | TNK2 (0.75) | SYKBRD4TNK2CHEK1JAK2 | |
| SCHEMBL24255222 | 0.72 | TNK2 (0.75) | SYKBRD4TNK2CHEK1JAK2 | |
| SCHEMBL655466 | 0.71 | SYK (1.00) | SYKSTK17AJAK2LCKROS1 | |
| SCHEMBL1935532 | 0.71 | PRKCQ (0.54) | STK17ASTK17BLRRK2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129222-A1 | DIAMINOPYRIMIDINES AS FUNGICIDES | Bayer CropScience AG (DE) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008107096-A1 | DIAMINOPYRIMIDINES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2008-09-12 | — | — | WO | disclosed |