Methylparaben

Methylparaben

SCHEMBL4440

COC(=O)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 1.00
CA2 P00918 8/20 1.00
CA12 O43570 5/20 1.00
CA7 P43166 5/20 1.00
CA9 Q16790 5/20 1.00
CA14 Q9ULX7 5/20 1.00
ALDH1A1 P00352 4/20 0.69
LMNA P02545 1/20 0.69
GAA P10253 1/20 0.69
TDP1 Q9NUW8 2/20 0.67
TSHR P16473 2/20 0.62
MAPT P10636 2/20 0.59
ESR1 P03372 2/20 0.59
XDH P47989 1/20 0.59
ESR2 Q92731 1/20 0.59
LOXL2 Q9Y4K0 1/20 0.57
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
CHRM1 P11229 1/20 0.55
SLC6A2 P23975 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylparaben SCHEMBL321534 1.00 CA1 (1.00) CA1CA2CA12CA7CA9
Methylparaben SCHEMBL48757 0.98 CA1 (0.95) CA1CA2CA12CA7CA9
Methylparaben SCHEMBL21274302 0.98 CA1 (0.95) CA1CA2CA12CA7CA9
Methylparaben SCHEMBL1699480 0.98 CA1 (0.95) CA1CA2CA12CA7CA9
Methylparaben SCHEMBL16029235 0.98 CA1 (0.95) CA1CA2CA12CA7CA9
Methylparaben SCHEMBL2810862 0.98 CA1 (0.95) CA1CA2CA12CA7CA9
Methylparaben SCHEMBL475867 0.98 CA1 (0.95) CA1CA2CA12CA7CA9
Methylparaben SCHEMBL8779118 0.98 CA1 (0.95) CA1CA2CA12CA7CA9
Methylparaben SCHEMBL6315862 0.98 CA1 (0.95) CA1CA2CA12CA7CA9
Methylparaben SCHEMBL31713879 0.98 CA1 (0.95) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 371148 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119214963-A Camellia oil anti-wrinkle, anti-aging and antioxidant facial cream and preparation method thereof 湖南金昌生物技术有限公司 2024-12-31 CN claimed
CN-118903535-B Composition containing plant extract and application thereof 安徽本森堂生物科技有限公司 2024-12-13 CN claimed
WO-2024239469-A1 PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR, EXTERNAL FORMULATION, AND USE THEREOF 凌科药业(杭州)有限公司 2024-11-28 WO claimed
US-12150920-B2 Topical pharmaceutical composition in the form of aqueous gel comprising at least amitriptyline ALGOTHERAPEUTIX (FR) 2024-11-26 US claimed
CN-115957370-B Scar repairing silica gel and preparation method thereof 振德医疗用品股份有限公司 2024-11-26 CN claimed
CN-113030340-B Method for measuring characteristic component content of bupleurum in bupleurum preparation by using high-resolution mass spectrum for liquid association 北京市药品检验研究院(北京市疫苗检验中心) 2024-11-26 CN claimed
CN-119015163-A Application of hydroxypropyl cassia gum in preparing tooth whitening agent, tooth whitening composition and anhydrous toothpaste 广州市倩采化妆品有限公司 2024-11-26 CN claimed
CN-118975981-A Ziprasidone hydrochloride suspension and preparation method thereof 北京万全阳光医学技术有限公司 2024-11-19 CN claimed
CN-118975936-A Water aqua jelly stick-shaped product and preparation method thereof 上海绵花棠化妆品有限公司 2024-11-19 CN claimed
CN-116077372-B Water-in-oil type sun-proof dispersion system and preparation method and application thereof 湖北美凯化工有限公司 2024-11-15 CN claimed
US-4022199-A Method of preventing the spread and control of mastitis FETTY WALTER W 1977-05-10 US claimed
US-4020232-A COATINGS OF AN AMINE DERIVATIVE AND A LEUCO DYE CAPABLE OF REACTING WITH SAID AMINE MITSUBISHI PAPER MILLS, LTD. (JA) 1977-04-26 US claimed
US-3998753-A PHARMACOLOGICAL OR COSMETIC PREPARATIONS OR ANIMAL FEEDSTUFF HOFFMANN-LA ROCHE INC. (US) 1976-12-21 US claimed
US-3985892-A CREAMS JOUVEINAL S.A. (FR) 1976-10-12 US claimed
US-3984605-A Heat sensitive recording material containing decolorizing agent MITSUBISHI PAPER MILLS, LTD. (JA) 1976-10-05 US claimed
US-3981906-A Process for preparing alkyl 4,4'-(ethylenedioxy)bis-benzoates ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-09-21 US claimed
US-3960795-A Hydrolyzed reaction product of a polyepoxide with a phenolic compound having a group hydrolyzable to carboxyl PPG INDUSTRIES, INC. (US) 1976-06-01 US claimed
US-3954974-A Disinfectant for the surface of human body parts containing hydrogen peroxide HERZOG PAUL 1976-05-04 US claimed
US-3953608-A Cosmetic compositions for the skin containing a chitosan derivative L'OREAL (FR) 1976-04-27 US claimed
US-3950519-A Composition and method of treating asthma MORA PHARMACEUTICALS, INC. 1976-04-13 US claimed