SCHEMBL444005

SCHEMBL444005

N[C@H]1CCC(=O)NC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5202970 1.00
SCHEMBL528253 1.00
Hydrochloric Acid SCHEMBL33649 0.98 CRBN (0.44)
Hydrochloric Acid SCHEMBL19347669 0.98 CRBN (0.44)
Bromide SCHEMBL3546365 0.98 CRBN (0.44)
Hydrochloric Acid SCHEMBL22720839 0.98 CRBN (0.44)
Hydrochloric Acid SCHEMBL22720671 0.98 CRBN (0.44)
Bromide SCHEMBL3545017 0.98 CRBN (0.44)
Bromide SCHEMBL5203587 0.98 CRBN (0.44)
Hydrochloric Acid SCHEMBL283133 0.95 CRBN (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1353672-B1 SYNTHESIS OF 4-AMINO-THALIDOMIDE ENANTIOMERS CHILDRENS MEDICAL CENTER (US) 2007-10-03 EP claimed
EP-4722219-A1 CEREBELLAR PROTEIN E3 UBIQUITIN LIGASE INHIBITOR AND CHIMERIC COMPOUND TARGETING PROTEIN DEGRADATION Gan & Lee Pharmaceuticals Co., Ltd. (CN) 2026-04-08 EP disclosed
US-20260053796-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR ARVINAS OPERATIONS INC (US) 2026-02-26 US disclosed
US-20260028354-A1 TETRAHYDRONAPHTHALENE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS REGENT OF THE UNIV OF MICHIGAN (US) 2026-01-29 US disclosed
US-20260028346-A1 BTK DEGRADER AND USE THEREOF ASCENTAGE PHARMA SUZHOU CO LTD (CN) 2026-01-29 US disclosed
US-20260028345-A1 BTK DEGRADER AND USE THEREOF ASCENTAGE PHARMA SUZHOU CO LTD (CN) 2026-01-29 US disclosed
US-20260007681-A1 INDOLE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS UNIV MICHIGAN (US) 2026-01-08 US disclosed
EP-4652161-A1 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS Uppthera, Inc. (KR) 2025-11-26 EP disclosed
EP-4626555-A1 GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF Tiger Biotherapeutics Inc. (US) 2025-10-08 EP disclosed
EP-4626554-A1 GLUTARIMIDE-CONTAINING KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF Tiger Biotherapeutics Inc. (US) 2025-10-08 EP disclosed
US-20080306113-A1 Methods for treating macular degeneration using 4-(amino)-2-(2,6-dioxo(3-piperidyle))-isoindoline-1,3-dione CHILDREN'S MEDICAL CENTER CORPORATION, THE 2008-12-11 US disclosed
US-20080045557-A1 Administering chemokine peptides, variants, and derivatives thereof, as well as chemokine peptide analogs to modulate the migration or recruitment of leukocytes to a preselected physiological site CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LTD. 2008-02-21 US disclosed
EP-1353672-B1 SYNTHESIS OF 4-AMINO-THALIDOMIDE ENANTIOMERS CHILDRENS MEDICAL CENTER (US) 2007-10-03 EP disclosed
US-7238711-B1 Compounds and methods to inhibit or augment an inflammatory response CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LTD. (GB) 2007-07-03 US disclosed
WO-2006081251-A2 METHODS AND COMPOSITIONS USING 4-AMINO-2-(3-METHYL-2,6-DIOXOPIPERIDIN-3-YL)-ISOINDOLE-1-3-DIONE CELGENE CORPORATION (US) 2006-08-03 WO disclosed
WO-2004022536-A1 NEW HETEROCYCLIC AMIDE COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLENMARK PHARMACEUTICALS LIMITED (US) 2004-03-18 WO disclosed
US-6353084-B1 BIODEGRADABLE POLYMER OBTAINED BY REACTING MIXTURE OF ADIPIC ACID, TEREPHTHALIC ACID AND COMPOUND CONTAINING SULFONATE GROUPS WITH MIXTURE OF DIOL, ALKANOLAMINE, DIAMINOALKANE AND BISOXAZOLINE, AND POLYHYDROXY OR POLYCARBOXYLIC ACID COMPOUND BASF AKTIENGESELLSCHAFT (DE) 2002-03-05 US disclosed
US-6111058-A Biodegradable polyesteramide and a process of preparing BASF AKTIENGESELLSCHAFT (DE) 2000-08-29 US disclosed
US-5880220-A POLYETHERESTERAMIDES BASF AKTIENGESELLSCHAFT (DE) 1999-03-09 US disclosed
US-5863991-A Biodegradable polymers, the preparation thereof and the use thereof for the production of biodegradable moldings BASF AKTIENGESELLSCHAFT (DE) 1999-01-26 US disclosed