SCHEMBL4440055

SCHEMBL4440055

CN(C(=O)c1ccccc1C1CCN(CCN2C(=O)COc3ccccc32)CC1)c1ccncc1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 9/20 0.54
CHRM1 P11229 6/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4885364 0.83 UTS2R (0.56) UTS2RCHRM1
SCHEMBL4889112 0.82 UTS2R (0.61) UTS2RCHRM1
SCHEMBL4426643 0.82 UTS2R (0.62) UTS2RCHRM1
SCHEMBL4886089 0.82 UTS2R (0.54) UTS2RCHRM1
SCHEMBL4430430 0.81 UTS2R (0.64) UTS2RCHRM1
SCHEMBL27775609 0.81 UTS2R (0.67) UTS2RCHRM1
SCHEMBL4563479 0.80 UTS2R (0.53) UTS2RCHRM1
SCHEMBL4431689 0.80 UTS2R (0.60) UTS2RCHRM1
SCHEMBL4437097 0.78 UTS2R (0.67) UTS2RCHRM1
SCHEMBL4431814 0.78 UTS2R (0.68) UTS2RCHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2049120-A1 UROTENSIN II RECEPTOR ANTAGONISTS Janssen Pharmaceutica, N.V. (BE) 2009-04-22 EP claimed
WO-2008016534-A1 UROTENSIN II RECEPTOR ANTAGONISTS JANSSEN PHARMACEUTICA, N.V. (BE) 2008-02-07 WO claimed