Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.43 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4554528 | 0.92 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL4554530 | 0.85 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL2816485 | 0.83 | MAPT (0.44) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL4554526 | 0.82 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL2813789 | 0.78 | MEN1 (0.54) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL2815993 | 0.76 | CFTR (0.52) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL2814726 | 0.74 | KMT2A (0.58) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL2816819 | 0.72 | MEN1 (0.63) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL4556123 | 0.72 | KCNQ3 (0.42) | MEN1KMT2ANPC1TP53SMN1; SMN2 | |
| SCHEMBL4439127 | 0.71 | HPSE (0.49) | MEN1KMT2ANPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |