Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149561 | 0.87 | EPHX1 (0.59) | EPHX1DPP7ZDHHC20ZDHHC2PLA2G2A | |
| SCHEMBL153838 | 0.87 | EPHX1 (0.59) | EPHX1DPP7ZDHHC20ZDHHC2PLA2G2A | |
| SCHEMBL150597 | 0.87 | EPHX1 (0.59) | EPHX1DPP7ZDHHC20ZDHHC2PLA2G2A | |
| SCHEMBL146327 | 0.87 | EPHX1 (0.59) | EPHX1DPP7ZDHHC20ZDHHC2PLA2G2A | |
| SCHEMBL144546 | 0.87 | EPHX1 (0.59) | EPHX1DPP7ZDHHC20ZDHHC2PLA2G2A | |
| SCHEMBL372894 | 0.87 | EPHX1 (0.59) | EPHX1DPP7ZDHHC20ZDHHC2PLA2G2A | |
| SCHEMBL14857009 | 0.87 | EPHX1 (0.59) | EPHX1DPP7ZDHHC20ZDHHC2PLA2G2A | |
| SCHEMBL149423 | 0.87 | EPHX1 (0.59) | EPHX1DPP7ZDHHC20ZDHHC2PLA2G2A | |
| SCHEMBL148882 | 0.87 | EPHX1 (0.59) | EPHX1DPP7ZDHHC20ZDHHC2PLA2G2A | |
| SCHEMBL146693 | 0.87 | EPHX1 (0.59) | EPHX1DPP7ZDHHC20ZDHHC2PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835368-B2 | Compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120065110-A1 | Compounds and a Method of Lubricating an Internal Combustion Engine | THE LUBRIZOL CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |