Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440382 | 1.00 | TSHR (0.60) | TSHR | |
| SCHEMBL8532404 | 0.88 | TSHR (0.47) | TSHR | |
| SCHEMBL155325 | 0.78 | — | — | |
| SCHEMBL215673 | 0.78 | — | — | |
| SCHEMBL214876 | 0.78 | — | — | |
| SCHEMBL155326 | 0.78 | — | — | |
| Cyanide SCHEMBL3983478 | 0.73 | — | — | |
| Acetonitrile SCHEMBL27598600 | 0.73 | — | — | |
| Cyanide SCHEMBL27742508 | 0.73 | — | — | |
| SCHEMBL15992848 | 0.69 | TSHR (0.62) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041074-A2 | HYDROCYANATION OF 2-PENTENENITRILE | Invista Technologies S.a.r.l. (CH) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008008927-A2 | HYDROCYANATION OF 2-PENTENENITRILE | INVISTA TECHNOLOGIES S.A.R.L. (CH) | 2008-01-17 | — | — | WO | disclosed |
| US-6355833-B2 | HYDROCYANATION OF BUTADIENE TO ADIPONITRILE | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-12 | — | — | US | disclosed |
| US-20010014647-A1 | Catalyst comprising at least one nickel(0) complex based on a phosphonite ligand, and the preparation of nitriles | FISCHER JAKOB (DE) | 2001-08-16 | — | — | US | disclosed |