SCHEMBL444076

SCHEMBL444076

CCOC(=O)C(CC)(CC)CC

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.63
CYP4A11 Q02928 3/20 0.63
ALDH1A1 P00352 3/20 0.48
LMNA P02545 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ALOX15 P16050 1/20 0.43
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
SOAT1 P35610 1/20 0.43
PKM P14618 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
THRB P10828 1/20 0.42
HTT P42858 1/20 0.41
TRPA1 O75762 1/20 0.40
PIN1 Q13526 1/20 0.39
MMP8 P22894 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL49875 0.97 CYP4F2 (0.61) CYP4F2CYP4A11ALDH1A1LMNAHSD17B10
SCHEMBL28872935 0.97 CYP4F2 (0.61) CYP4F2CYP4A11ALDH1A1LMNAHSD17B10
SCHEMBL11001997 0.97 CYP4F2 (0.61) CYP4F2CYP4A11ALDH1A1LMNAHSD17B10
Ammonia Solution, Strong SCHEMBL8176760 0.95 CYP4F2 (0.59) CYP4F2CYP4A11ALDH1A1LMNAHSD17B10
Bromide SCHEMBL25233680 0.95 CYP4F2 (0.59) CYP4F2CYP4A11ALDH1A1LMNAHSD17B10
Ethylenediamine SCHEMBL3498869 0.91 CYP4F2 (0.55) CYP4F2CYP4A11ALDH1A1LMNAHSD17B10
SCHEMBL504042 0.91 CYP4F2 (0.55) CYP4F2CYP4A11ALDH1A1LMNAHSD17B10
Trimethylammonium SCHEMBL27722697 0.91 CYP4F2 (0.55) CYP4F2CYP4A11ALDH1A1LMNAHSD17B10
SCHEMBL20512103 0.87 CYP4F2 (0.62) CYP4F2CYP4A11ALDH1A1LMNAHSD17B10
SCHEMBL5000137 0.87 CYP4F2 (0.62) CYP4F2CYP4A11ALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115992021-A Use of boron-containing additives as lead corrosion inhibitors 卡斯特罗尔有限公司 2023-04-21 CN claimed
CN-110157413-B Aggregation-induced emission molecular probe for selectively identifying lead ions and aluminum ions, and preparation method and application thereof 浙江师范大学 2022-11-15 CN claimed
CN-113042344-A Surface smoothing processing technology applied to natural stone processing 邵阳市联合农林建材科技有限公司 2021-06-29 CN claimed
CN-112980005-A Quasi-spherical particles and preparation method and application thereof 中国科学院大连化学物理研究所 2021-06-18 CN claimed
CN-110358069-A A kind of main chain polyester containing selenium and preparation method thereof 浙江大学 2019-10-22 CN claimed
CN-109180937-A A method of preparing aliphatic poly thioether 浙江大学 2019-01-11 CN claimed
US-8529955-B2 Methods of treatment using a gastric retained gabapentin dosage DEPOMED, INC. (US) 2013-09-10 US claimed
US-8475813-B2 Methods of treatment using a gastric retained gabapentin dosage DEPOMED, INC. (US) 2013-07-02 US claimed
US-8440232-B2 Methods of treatment using a gastric retained gabapentin dosage DEPOMED, INC. (US) 2013-05-14 US claimed
US-20120064168-A1 METHODS OF TREATMENT USING A GASTRIC RETAINED GABEPENTIN DOSAGE DEPOMED, INC. (US) 2012-03-15 US claimed
WO-2003078045-A2 MICROCAPILLARY HYBRIDIZATION CHAMBER SYNGENTA PARTICIPATIONS AG (CH) 2003-09-25 WO claimed
WO-1997043450-A1 HYBRIDIZATION ASSAYS ON OLIGONUCLEOTIDE ARRAYS AFFYMETRIX, INC. (US) 1997-11-20 WO claimed
US-5362902-A Diuretics and treatment of cardiovascular disorders PFIZER INC. (US) 1994-11-08 US claimed
EP-0342850-B1 ENANTIOMERIC GLUTARAMIDE DIURETIC AGENTS Pfizer Limited (GB) 1992-05-20 EP claimed
EP-0274234-B1 SPIRO-SUBSITUTED GLUTARAMIDE DIURETIC AGENTS Pfizer Limited (GB) 1991-09-11 EP claimed
US-5030654-A Glutaramide diuretic agents PFIZER INC. (US) 1991-07-09 US claimed
WO-1991007378-A1 CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS PFIZER LIMITED (GB) 1991-05-30 WO claimed
EP-0343911-A2 Cycloalkyl-substituted glutaramide diuretic agents Pfizer Limited (GB) 1989-11-29 EP claimed
EP-0342850-A1 Enantiomeric glutaramide diuretic agents Pfizer Limited (GB) 1989-11-23 EP claimed
EP-0274234-A2 Spiro-subsituted glutaramide diuretic agents Pfizer Limited (GB) 1988-07-13 EP claimed