Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1822592 | 0.82 | NPSR1 (0.47) | NPSR1ALDH1A1HTTKMT2AF2 | |
| SCHEMBL29931026 | 0.81 | NPSR1 (0.58) | NPSR1ALDH1A1HTTCTSDPLAU | |
| SCHEMBL1695081 | 0.81 | NPSR1 (0.58) | NPSR1ALDH1A1HTTCTSDPLAU | |
| SCHEMBL22204543 | 0.78 | NPSR1 (0.51) | NPSR1ALDH1A1HTTCTSDKMT2A | |
| SCHEMBL19222047 | 0.77 | NPSR1 (0.53) | NPSR1ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL14524137 | 0.77 | NPSR1 (0.53) | NPSR1ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL7176676 | 0.76 | MAPT (0.46) | NPSR1ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL27904894 | 0.76 | NPSR1 (0.47) | NPSR1ALDH1A1HTTCTSDKMT2A | |
| SCHEMBL30408992 | 0.74 | NPSR1 (0.55) | NPSR1ALDH1A1HTTCTSDKMT2A | |
| SCHEMBL27797941 | 0.74 | NPSR1 (0.48) | NPSR1ALDH1A1HTTKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009148961-A2 | DRUGS TO PREVENT HPV INFECTION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-12-10 | — | — | WO | disclosed |