Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 3/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441005 | 1.00 | DPP4 (0.44) | DPP4DPP8DPP9ATMPRSS1 | |
| SCHEMBL29734330 | 0.88 | DPP4 (0.38) | DPP4DPP8DPP9ACE | |
| SCHEMBL30069123 | 0.88 | DPP4 (0.38) | DPP4DPP8DPP9ACE | |
| SCHEMBL11329668 | 0.85 | ATM (0.39) | ATMPRSS1TMPRSS15ACE | |
| SCHEMBL24322780 | 0.84 | F2 (0.42) | DPP4PRSS1 | |
| SCHEMBL8277398 | 0.82 | DPP4 (0.65) | DPP4DPP8DPP9 | |
| SCHEMBL15434853 | 0.82 | DPP4 (0.65) | DPP4DPP8DPP9 | |
| SCHEMBL2114959 | 0.81 | ACE (0.46) | DPP4DPP8DPP9ACE | |
| SCHEMBL3451623 | 0.81 | ACE (0.46) | DPP4DPP8DPP9ACE | |
| SCHEMBL2114955 | 0.81 | ACE (0.46) | DPP4DPP8DPP9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2117536-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | Beiersdorf AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008101693-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | BEIERSDORF AG (DE) | 2008-08-28 | — | — | WO | disclosed |