Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | PEPD | P12955 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2983236 | 1.00 | CHRM2 (0.47) | CHRM2CHRM4CHRM3PEPDACE | |
| SCHEMBL2983239 | 1.00 | CHRM2 (0.47) | CHRM2CHRM4CHRM3PEPDACE | |
| SCHEMBL596154 | 1.00 | CHRM2 (0.47) | CHRM2CHRM4CHRM3PEPDACE | |
| SCHEMBL596152 | 1.00 | CHRM2 (0.47) | CHRM2CHRM4CHRM3PEPDACE | |
| SCHEMBL596153 | 1.00 | CHRM2 (0.47) | CHRM2CHRM4CHRM3PEPDACE | |
| SCHEMBL17816439 | 1.00 | CHRM2 (0.47) | CHRM2CHRM4CHRM3PEPDACE | |
| Ammonia Solution, Strong SCHEMBL1639042 | 0.98 | CHRM2 (0.46) | CHRM2CHRM4CHRM3PEPDACE | |
| SCHEMBL15590800 | 0.95 | SLC6A2 (0.46) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL30850208 | 0.95 | SLC6A2 (0.46) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL2952999 | 0.95 | SLC6A2 (0.46) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882740-A1 | IAP ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2015-06-17 | — | — | EP | disclosed |
| US-20150158021-A1 | PROCESS FOR THE IMMOBILIZATION OF CATALYSTS ON TEXTILE MATERIALS, THE OBTAINED TEXTILE MATERIALS AND THE USE OF SAID MATERIALS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-06-11 | — | — | US | disclosed |
| WO-2014025759-A1 | IAP ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-02-13 | — | — | WO | disclosed |
| EP-2134716-A1 | PYRROLOTRIAZINE KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008131050-A1 | PYRROLOTRIAZINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158021-A1 | PROCESS FOR THE IMMOBILIZATION OF CATALYSTS ON TEXTILE MATERIALS, THE OBTAINED TEXTILE MATERIALS AND THE USE OF SAID MATERIALS | LIG4, DDT, MCM4 | CHRM2 1113/4885CHRM4 115/4885CHRM3 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.