Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449110 | 1.00 | EGFR (0.73) | EGFRERBB2 | |
| SCHEMBL4449261 | 0.92 | EGFR (0.76) | EGFR | |
| SCHEMBL4441248 | 0.92 | EGFR (0.76) | EGFR | |
| SCHEMBL4449173 | 0.91 | EGFR (0.71) | EGFRERBB2 | |
| SCHEMBL4454338 | 0.90 | EGFR (0.75) | EGFRERBB2 | |
| SCHEMBL4447202 | 0.90 | EGFR (0.75) | EGFRERBB2 | |
| SCHEMBL4446930 | 0.89 | EGFR (0.70) | EGFRERBB2 | |
| SCHEMBL4443442 | 0.89 | EGFR (0.74) | EGFR | |
| SCHEMBL4454616 | 0.89 | EGFR (0.74) | EGFR | |
| SCHEMBL4449139 | 0.89 | EGFR (0.67) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632840-B2 | Quinazoline compounds for the treatment of hyperproliferative disorders | ASTRAZENECA AB (SE) | 2009-12-15 | — | — | US | disclosed |