SCHEMBL4444950

SCHEMBL4444950

C=CCOC(F)(F)C(F)(F)C(F)(F)C(C)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11276772 0.86
SCHEMBL17669766 0.84
SCHEMBL11277300 0.84
SCHEMBL2053381 0.82
SCHEMBL17192459 0.80
SCHEMBL996542 0.80
SCHEMBL6665277 0.80
SCHEMBL3135164 0.79
SCHEMBL5566076 0.76
SCHEMBL8814534 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112823184-A Method for producing transparent polyimide film 株式会社钟化 2021-05-18 CN disclosed
CN-105666752-B A kind of fluorine silicon mold release agent composition altogether 衢州氟硅技术研究院 2019-05-14 CN disclosed
CN-106182514-B A kind of curable epoxide type fluoro-containing composition 怀化学院 2019-03-29 CN disclosed
CN-109016278-A Release agent and atomizing release agent 怀化学院 2018-12-18 CN disclosed
WO-2009085642-A1 TRIMETHYLSILYL-CAPPED POLYSILOXANE MACROMONOMERS CONTAINING POLAR FLUORINATED SIDE-CHAINS BAUSCH & LOMB INCORPORATED (US) 2009-07-09 WO disclosed
US-20090168013-A1 Trimethylsilyl-Capped Polysiloxane Macromonomers Containing Polar Fluorinated Side-Chains BAUSCH & LOMB INCORPORATED 2009-07-02 US disclosed
EP-1877856-A1 PHOTOCHROMIC BLUE LIGHT FILTERING MATERIALS AND OPHTHALMIC DEVICES Bausch & Lomb Incorporated (US) 2008-01-16 EP disclosed
EP-1539196-B1 VITREORETINAL TAMPONADES BASED ON FLUOROSILICONE FLUIDS BAUSCH & LOMB (US) 2007-12-05 EP disclosed
EP-1811958-A2 REMOVAL OF IMPURITIES WITH SUPERCRITICAL FLUIDS FROM OCULAR DRUG DELIVERY DEVICES DURING MANUFACTURING Bausch & Lomb Incorporated (US) 2007-08-01 EP disclosed
US-20070159594-A9 Photochromic blue light filtering materials and ophthalmic devices BAUSCH & LOMB INCORPORATED 2007-07-12 US disclosed
US-5714557-A UNSATURATED FLUORINATED ACRYLIC ESTER- OR AMIDE-CAPPED POLYSILOXANES AND DISILOXANES; CONTACT LENSES; FILMS; YOUNG'S MODULUS OF ELASTICIY; NONHYDROLYZING; MEDICAL EQUIPMENT BAUSCH & LOMB INCORPORATED (US) 1998-02-03 US disclosed
US-5710302-A Monomeric units useful for reducing the modules of silicone hydrogels BAUSCH & LOMB INCORPORATED (US) 1998-01-20 US disclosed
EP-0683799-B1 FLUOROSILICONE HYDROGELS BAUSCH & LOMB (US) 1997-12-29 EP disclosed
WO-1997020852-A1 MONOMERIC UNITS USEFUL FOR REDUCING THE MODULUS OF SILICONE HYDROGELS BAUSCH & LOMB INCORPORATED (US) 1997-06-12 WO disclosed
WO-1997020851-A1 MONOMERIC UNITS USEFUL FOR REDUCING THE MODULUS OF LOW WATER POLYMERIC SILICONE COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 1997-06-12 WO disclosed
US-5539016-A POLYMERS FOR CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 1996-07-23 US disclosed
EP-0683799-A1 FLUOROSILICONE HYDROGELS BAUSCH &amp; LOMB INCORPORATED (US) 1995-11-29 EP disclosed
US-5387662-A For contact lenses; acrylated polysiloxanes BAUSCH & LOMB INCORPORATED (US) 1995-02-07 US disclosed
WO-1994018253-A1 FLUOROSILICONE HYDROGELS BAUSCH & LOMB INCORPORATED (US) 1994-08-18 WO disclosed
US-5321108-A Improving solubility of unsaturated siloxane monomers in hydrophilic monomer BAUSCH & LOMB INCORPORATED (US) 1994-06-14 US disclosed