Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12961196 | 0.90 | F10 (0.82) | F10KCNH2 | |
| SCHEMBL14148715 | 0.90 | F10 (1.00) | F10KCNH2 | |
| SCHEMBL1051324 | 0.90 | F10 (1.00) | F10KCNH2 | |
| SCHEMBL4442235 | 0.90 | F10 (0.81) | F10KCNH2 | |
| SCHEMBL4447896 | 0.88 | F10 (1.00) | F10 | |
| SCHEMBL1027621 | 0.87 | F10 (0.85) | F10KCNH2 | |
| SCHEMBL2253925 | 0.87 | F10 (0.85) | F10KCNH2 | |
| SCHEMBL2251421 | 0.87 | F10 (0.85) | F10KCNH2 | |
| SCHEMBL3449372 | 0.87 | F10 (0.78) | F10KCNH2 | |
| SCHEMBL4441855 | 0.86 | F10 (1.00) | F10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550487-B2 | Pyrrolidine-3,4-dicarboxamide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-06-23 | — | — | US | disclosed |
| EP-1732918-B1 | NOVEL PYRROLIDINE-3,4-DICARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-11-12 | — | — | EP | disclosed |
| EP-1732918-A1 | NOVEL PYRROLIDINE-3,4-DICARBOXAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092881-A1 | NOVEL PYRROLIDINE-3,4-DICARBOXAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-10-06 | — | — | WO | disclosed |