Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.36 |
| ▸ | CTSL | P07711 | 5/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1450725 | 0.83 | TRPV1 (0.44) | TRPV1 | |
| SCHEMBL1450728 | 0.83 | TRPV1 (0.44) | TRPV1 | |
| SCHEMBL3603202 | 0.83 | TRPV1 (0.42) | TRPV1CTSLCTSVCTSBCYP3A4 | |
| SCHEMBL3592359 | 0.81 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL3599187 | 0.79 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL1451749 | 0.79 | TRPV1 (0.38) | TRPV1CTSLCTSVCTSBCYP3A4 | |
| SCHEMBL1451741 | 0.79 | TRPV1 (0.38) | TRPV1CTSLCTSVCTSBCYP3A4 | |
| SCHEMBL1451139 | 0.79 | TRPV1 (0.39) | TRPV1CTSLCTSVCTSBCYP3A4 | |
| SCHEMBL3600347 | 0.79 | TRPV1 (0.42) | TRPV1 | |
| SCHEMBL1451625 | 0.78 | TRPV1 (0.45) | TRPV1CTSLCTSVCTSBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |