Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 18/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807204 | 0.85 | GCK (0.37) | GCKKCNH2ABL1 | |
| SCHEMBL12807221 | 0.84 | GCK (0.37) | GCKKCNH2ABL1 | |
| SCHEMBL1077325 | 0.83 | GCK (0.38) | GCKKCNH2ABL1 | |
| SCHEMBL1677219 | 0.83 | GCK (0.39) | GCKKCNH2ABL1 | |
| SCHEMBL1677335 | 0.82 | GCK (0.39) | GCKKCNH2ABL1 | |
| SCHEMBL1677365 | 0.81 | GCK (0.39) | GCKKCNH2ABL1 | |
| SCHEMBL12806848 | 0.81 | GCK (0.40) | GCKKCNH2ABL1 | |
| SCHEMBL1076029 | 0.81 | GCK (0.38) | GCKKCNH2ABL1 | |
| SCHEMBL1076656 | 0.81 | GCK (0.38) | GCKKCNH2ABL1 | |
| SCHEMBL1076539 | 0.80 | GCK (0.42) | GCKKCNH2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125873-A1 | FUSED RING COMPOUNDS AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-15 | — | — | WO | disclosed |