SCHEMBL4446330

SCHEMBL4446330

Br[Mg]C1=C(C=Cc2ccccc2)CCC1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FGF23 Q9GZV9 3/20 0.53
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAOB P27338 3/20 0.37
NFE2L2 Q16236 2/20 0.36
CYP19A1 P11511 2/20 0.36
MAOA P21397 2/20 0.36
CYP1A2 P05177 1/20 0.35
F3 P13726 1/20 0.35
CHAT P28329 2/20 0.34
HTT P42858 1/20 0.34
TRPA1 O75762 2/20 0.33
RELA Q04206 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL22712863 0.67 MAOB (0.73) MEN1KMT2AALDH1A1MAOBNFE2L2
(Z)-1,2-Diphenylethene SCHEMBL442 0.67 MAOB (0.73) MEN1KMT2AALDH1A1MAOBNFE2L2
(Z)-1,2-Diphenylethene SCHEMBL9488275 0.67 MAOB (0.73) MEN1KMT2AALDH1A1MAOBNFE2L2
(Z)-1,2-Diphenylethene SCHEMBL443 0.67 MAOB (0.73) MEN1KMT2AALDH1A1MAOBNFE2L2
(Z)-1,2-Diphenylethene SCHEMBL9134296 0.67 MAOB (0.73) MEN1KMT2AALDH1A1MAOBNFE2L2
(Z)-1,2-Diphenylethene SCHEMBL9488270 0.67 MAOB (0.73) MEN1KMT2AALDH1A1MAOBNFE2L2
(Z)-1,2-Diphenylethene SCHEMBL347707 0.67 MAOB (0.73) MEN1KMT2AALDH1A1MAOBNFE2L2
(Z)-1,2-Diphenylethene SCHEMBL9134305 0.67 MAOB (0.73) MEN1KMT2AALDH1A1MAOBNFE2L2
(Z)-1,2-Diphenylethene SCHEMBL21847984 0.67 MAOB (0.73) MEN1KMT2AALDH1A1MAOBNFE2L2
SCHEMBL1610005 0.65 MAOB (0.55) FGF23MEN1KMT2AALDH1A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629494-B2 Process for producing cyclopropylphenol derivative MITSUI CHEMICALS AGRO, INC. (JP) 2009-12-08 US disclosed
US-20090054681-A1 Production Process of cyclopropylphenol derivatives SANKYO AGRO COMPANY, LIMITED (JP) 2009-02-26 US disclosed
EP-1880987-A1 PROCESS FOR PRODUCING CYCLOPROPYLPHENOL DERIVATIVE Sankyo Agro Company, Limited (JP) 2008-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054681-A1 Production Process of cyclopropylphenol derivatives CBR3, CYP4X1, CYP4A11 FGF23 3016/4885MEN1 4580/4885KMT2A 3161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.