Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 11/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4446800 | 1.00 | KCNH2 (0.41) | KCNH2SLC2A1DPP4DPP7 | |
| SCHEMBL3547853 | 0.95 | KCNH2 (0.42) | KCNH2SLC2A1DPP4DPP7 | |
| SCHEMBL3547850 | 0.95 | KCNH2 (0.42) | KCNH2SLC2A1DPP4DPP7 | |
| SCHEMBL3547857 | 0.95 | KCNH2 (0.42) | KCNH2SLC2A1DPP4DPP7 | |
| SCHEMBL13315161 | 0.91 | KCNH2 (0.41) | KCNH2SLC2A1DPP4DPP7 | |
| SCHEMBL14610950 | 0.84 | KCNH2 (0.52) | KCNH2SLC2A1 | |
| SCHEMBL4443859 | 0.83 | KCNH2 (0.44) | KCNH2SLC2A1 | |
| SCHEMBL4214051 | 0.82 | KCNH2 (0.44) | KCNH2SLC2A1 | |
| SCHEMBL13382426 | 0.78 | KCNH2 (0.49) | KCNH2SLC2A1 | |
| SCHEMBL1076139 | 0.77 | SLC2A1 (0.42) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128019-A1 | TRICYCLIC ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2009-10-22 | — | — | WO | disclosed |