Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 3/20 | 0.34 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3595447 | 0.79 | HDAC6 (0.40) | NPBWR1CETPMCHR1P2RX3 | |
| SCHEMBL3595443 | 0.79 | HDAC6 (0.40) | NPBWR1CETPMCHR1P2RX3 | |
| SCHEMBL3587179 | 0.78 | CETP (0.41) | NPBWR1CETPGRIN1GRIN2BMCHR1 | |
| SCHEMBL3587178 | 0.78 | CETP (0.41) | NPBWR1CETPGRIN1GRIN2BMCHR1 | |
| SCHEMBL3587995 | 0.77 | CETP (0.44) | NPBWR1CETPGRIN1GRIN2BMCHR1 | |
| SCHEMBL3587999 | 0.77 | CETP (0.44) | NPBWR1CETPGRIN1GRIN2BMCHR1 | |
| SCHEMBL3588925 | 0.72 | GAA (0.37) | NPBWR1MCHR1 | |
| SCHEMBL3588919 | 0.72 | GAA (0.37) | NPBWR1MCHR1 | |
| SCHEMBL3601641 | 0.72 | IDH1 (0.38) | NPBWR1CETPMCHR1 | |
| SCHEMBL3601645 | 0.72 | IDH1 (0.38) | NPBWR1CETPMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | claimed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | claimed |
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |