⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529160 | 0.78 | — | — | |
| SCHEMBL10753481 | 0.75 | — | — | |
| SCHEMBL4977285 | 0.72 | — | — | |
| SCHEMBL7592069 | 0.72 | TDP1 (0.33) | — | |
| SCHEMBL703710 | 0.71 | — | — | |
| SCHEMBL2260309 | 0.71 | — | — | |
| SCHEMBL15128076 | 0.71 | — | — | |
| SCHEMBL7158109 | 0.69 | — | — | |
| SCHEMBL323645 | 0.69 | — | — | |
| Diethyl Sulfide SCHEMBL30738965 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006099957-A1 | INSECTICIDAL AND ACARICIDAL ANILINOTRIAZOLES | BAYER CROPSCIENCE AG (DE) | 2006-09-28 | — | — | WO | claimed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| EP-4172351-A1 | RECOMBINANT MODIFIED FIBROBLAST GROWTH FACTORS AND THERAPEUTIC USES THEREOF | Trefoil Therapeutics, Inc. (US) | 2023-05-03 | — | — | EP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| WO-2021263134-A1 | RECOMBINANT MODIFIED FIBROBLAST GROWTH FACTORS AND THERAPEUTIC USES THEREOF | TREFOIL THERAPEUTICS, INC. (US) | 2021-12-30 | — | — | WO | disclosed |
| US-20210309619-A1 | ISOXAZOLIN-5-ONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-10-07 | — | — | US | disclosed |
| US-11109593-B2 | Isoxazolin-5-one derivative and herbicide containing same as active ingredient | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-09-07 | — | — | US | disclosed |
| EP-3828176-A1 | ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | Hokko Chemical Industry Co., Ltd. (JP) | 2021-06-02 | — | — | EP | disclosed |
| US-20200267985-A1 | ISOXAZOLIN-5-ONE DERIVATIVE AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-08-27 | — | — | US | disclosed |
| WO-2020022350-A1 | ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | 北興化学工業株式会社 | 2020-01-30 | — | — | WO | disclosed |
| US-4355184-A | BY REACTING AN ALDEHYDE WITH AN ALKALI METAL SALT OF ACETOACETIC | NIPPON SODA COMPANY LIMITED (JP) | 1982-10-19 | — | — | US | disclosed |
| EP-0008058-B1 | N-AMINO-3,4,5-TRIHYDROXYPIPERIDINES, METHODS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, METHOD FOR THE PRODUCTION OF THE MEDICAMENTS AND ANIMAL FEEDSTUFF CONTAINING SAID COMPOUNDS | BAYER AG (DE) | 1982-08-18 | — | — | EP | disclosed |
| US-4293551-A | N-Amino-3,4,5-trihydroxypiperidines, their production and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |
| US-4260622-A | Animal feedstuffs employing 3,4,5-trihydroxypiperidines | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4199572-A | DERIVATIVES OF SISOMICINS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-04-22 | — | — | US | disclosed |
| US-4101583-A | Alpha-methylthio-alpha-(2-aminophenyl) acetaldehyde diloweralkyl acetals | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4080341-A | Carbazolenine and indole compounds | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-4067875-A | Certain N-phenyl or N-pyridyl aza sulfonium salts | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-3992392-A | Synthesis of indoles from anilines and intermediates therein | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3931331-A | PLANT PROTECTION INTERMEDIATES | ALLIED CHEMICAL CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |