SCHEMBL4447276

SCHEMBL4447276

C=C(C)C(=O)OCCOc1ccc(-c2ccc(OCCOC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.61
APEX1 P27695 1/20 0.61
HTT P42858 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
THRB P10828 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.44
RARB P10826 5/20 0.44
TSHR P16473 2/20 0.43
MAPT P10636 2/20 0.43
GAA P10253 1/20 0.43
HDAC3 O15379 3/20 0.42
HDAC4 P56524 3/20 0.42
HDAC1 Q13547 3/20 0.42
HDAC7 Q8WUI4 3/20 0.42
HDAC2 Q92769 3/20 0.42
HDAC10 Q969S8 3/20 0.42
HDAC11 Q96DB2 3/20 0.42
HDAC8 Q9BY41 3/20 0.42
HDAC6 Q9UBN7 3/20 0.42
HDAC9 Q9UKV0 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL454606 0.95 POLB (0.67) POLBAPEX1HTTTDP1THRB
SCHEMBL18308843 0.94 POLB (0.56) POLBAPEX1HTTTDP1THRB
SCHEMBL9807301 0.94 POLB (0.59) POLBAPEX1HTTTDP1THRB
SCHEMBL1494215 0.94 POLB (0.56) POLBAPEX1HTTTDP1THRB
SCHEMBL18960047 0.94 POLB (0.59) POLBAPEX1HTTTDP1THRB
SCHEMBL25796361 0.92 TDP1 (0.55) POLBAPEX1HTTTDP1THRB
SCHEMBL14400544 0.92 HTT (0.73) POLBAPEX1HTTTDP1THRB
SCHEMBL23785546 0.91 HTT (0.77) POLBAPEX1HTTTDP1L3MBTL1
SCHEMBL20807028 0.91 POLB (0.53) POLBAPEX1HTTTDP1THRB
SCHEMBL19730207 0.91 POLB (0.53) POLBAPEX1HTTTDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118685069-A Photo-curing packaging ink and display device 武汉尚赛光电科技有限公司 2024-09-24 CN disclosed
US-20200301213-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2020-09-24 US disclosed
EP-3187514-B1 POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER TOKUYAMA DENTAL CORP (JP) 2020-07-29 EP disclosed
US-20190300472-A1 POLYMERIZABLE MONOMER, METHOD OF PRODUCING POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER TOKUYAMA DENTAL CORPORATION (JP) 2019-10-03 US disclosed
US-10344214-B2 Liquid crystal display device and method for manufacturing the same DIC CORPORATION (JP) 2019-07-09 US disclosed
EP-2842974-B1 COMPOUND HAVING FOUR POLYMERIZABLE GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2019-03-13 EP disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed
US-20180142155-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME DIC CORPORATION (JP) 2018-05-24 US disclosed
EP-2955570-B1 LIQUID CRYSTAL DISPLAY ELEMENT AND MANUFACTURING METHOD FOR SAME DAINIPPON INK & CHEMICALS (JP) 2018-03-28 EP disclosed
US-20170321122-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME DIC CORPORATION (JP) 2017-11-09 US disclosed
WO-2014106799-A2 BIS-GLYCIDYL METHACRYLATE MONOMERS FOR COMPOSITE RESIN FORMULATIONS FOR DENTAL USE, METHODS FOR PREPARING SAID MONOMERS, RESIN FORMULATIONS FOR DIRECT DENTAL RESTORATION COMPRISING THE SAME AND USES THEREOF CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (AR) 2014-07-10 WO disclosed
US-20130277609-A1 COMPOUND HAVING FOUR POLYMERIZABLE GROUPS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-10-24 US disclosed
US-20130277609-A1 COMPOUND HAVING FOUR POLYMERIZABLE GROUPS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-10-24 US disclosed
US-20130134354-A1 POLYMERIZABLE COMPOUND JNC PETROCHEMICAL CORPORATION (JP) 2013-05-30 US disclosed
US-20130134354-A1 POLYMERIZABLE COMPOUND JNC PETROCHEMICAL CORPORATION (JP) 2013-05-30 US disclosed
US-7604755-B2 Electroconductive resin composition and separator for fuel cell JAPAN COMPOSITE CO., LTD. (JP) 2009-10-20 US disclosed
US-20060240303-A1 Conductive resin composition and fuel cell separators JAPAN COMPOSITE CO., LTD. (JP) 2006-10-26 US disclosed
US-6852780-B2 Composition for optical material, optical material and lenses NOF CORPORATION (JP) 2005-02-08 US disclosed
US-20030047722-A1 Composition for optical material, optical material and lenses NOF CORPORATION (JP) 2003-03-13 US disclosed
EP-1271186-A1 COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL AND LENSES NOF CORPORATION (JP) 2003-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130134354-A1 POLYMERIZABLE COMPOUND CCNA1, H1-2, CCNT1 POLB 1393/4885APEX1 314/4885HTT 2138/4885
US-20190300472-A1 POLYMERIZABLE MONOMER, METHOD OF PRODUCING POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER CHRM1, CHRM2, H1-0 POLB 2838/4885APEX1 550/4885HTT 900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.