SCHEMBL44480

SCHEMBL44480

CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 4/20 0.45
HDAC3 O15379 3/20 0.44
HDAC4 P56524 3/20 0.44
HDAC1 Q13547 3/20 0.44
HDAC7 Q8WUI4 3/20 0.44
HDAC2 Q92769 3/20 0.44
HDAC10 Q969S8 3/20 0.44
HDAC11 Q96DB2 3/20 0.44
HDAC8 Q9BY41 3/20 0.44
HDAC6 Q9UBN7 3/20 0.44
HDAC9 Q9UKV0 3/20 0.44
HDAC5 Q9UQL6 3/20 0.44
NPSR1 Q6W5P4 2/20 0.40
TSHR P16473 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
SIRT1 Q96EB6 1/20 0.40
SIRT3 Q9NTG7 1/20 0.40
DGAT1 O75907 1/20 0.38
POLB P06746 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16765694 1.00 SIRT2 (0.45) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL29361802 1.00 SIRT2 (0.45) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL27529584 0.99 SIRT2 (0.44) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL118552 0.95 SIRT2 (0.49) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL29544944 0.95 SIRT2 (0.49) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL1395479 0.94 POLB (0.49) SIRT2HDAC3HDAC4HDAC1HDAC7
Bromide SCHEMBL5514450 0.93 SIRT2 (0.48) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL30056078 0.93 SIRT2 (0.48) SIRT2HDAC3HDAC4HDAC1HDAC7
Fluoride Ion SCHEMBL4594160 0.93 SIRT2 (0.48) SIRT2HDAC3HDAC4HDAC1HDAC7
SCHEMBL15769691 0.93 SIRT2 (0.48) SIRT2HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 22376 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094699-A Method for coupling dialkylamines and polypeptides 2026-05-26 CN claimed
CN-122080119-A Synthesis method of MC-Gly-Gly-Phe-Gly tetrapeptide linker 2026-05-26 CN claimed
CN-122079809-A Synthesis method of dipeptide linker of antibody coupling degradation agent 2026-05-26 CN claimed
CN-122071449-A Substituted biphenyl compounds and application thereof in synthesis of cola pyrroside 北京凯因格领生物技术有限公司 2026-05-22 CN claimed
CN-122071456-A Preparation method of cola pyrrosir 北京凯因格领生物技术有限公司 2026-05-22 CN claimed
CN-122057039-A Caffeic acid bovine serum albumin conjugate, preparation method and application thereof 天津科技大学 2026-05-19 CN claimed
CN-122036836-A Solid phase synthesis method of phosphorylation and FAM double-label and application thereof 常州新一产生命科技有限公司 2026-05-15 CN claimed
CN-122036615-A Indazole hydrazide compound and preparation method and application thereof 南京农业大学 2026-05-15 CN claimed
WO-2026099776-A1 A PROCESS FOR THE PREPARATION OF PACLITAXEL FRESENIUS KABI ONCOLOGY LTD. (IN) 2026-05-15 WO claimed
WO-2026098560-A2 BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-15 WO claimed
US-5916888-A Imidazo 1,5A!pyridine derived serine protease inhibitors AKZO NOBEL, N.V. (NL) 1999-06-29 US claimed
EP-0906296-A1 PROCESS FOR THE PREPARATION OF CHIRAL KETO-HETEROCYCLES OF BASIC AMINO ACIDS WARNER-LAMBERT COMPANY LLC (US) 1999-04-07 EP claimed
EP-0899267-A1 Disubstituted trans-3,4,4a,5,6,10b-hexahydro-2H-napht(1,2-b)-1,4-oxazines, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1999-03-03 EP claimed
WO-1998052923-A1 SYNTHESIS OF ACRIDINE DERIVATIVE MULTIDRUG-RESISTANT INHIBITORS GLAXO GROUP LIMITED (GB) 1998-11-26 WO claimed
EP-0877751-A1 LINKER ARM FOR SOLID SUPPORT OLIGONUCLEOTIDE SYNTHESIS AND PROCESS FOR PRODUCTION THEREOF UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) 1998-11-18 EP claimed
WO-1998042721-A1 URONIUM SALT CONJUGATE VACCINES LEES ANDREW (US) 1998-10-01 WO claimed
WO-1997048687-A1 PROCESS FOR THE PREPARATION OF CHIRAL KETO-HETEROCYCLES OF BASIC AMINO ACIDS WARNER-LAMBERT COMPANY (US) 1997-12-24 WO claimed
WO-1997023497-A1 LINKER ARM FOR SOLID SUPPORT OLIGONUCLEOTIDE SYNTHESIS AND PROCESS FOR PRODUCTION THEREOF UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) 1997-07-03 WO claimed
EP-0723554-A1 CYCLIC PEPTIDE TUBE THE SCRIPPS RESEARCH INSTITUTE (US) 1996-07-31 EP claimed
WO-1995010535-A1 CYCLIC PEPTIDE TUBE THE SCRIPPS RESEARCH INSTITUTE (US) 1995-04-20 WO claimed