Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.79 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.55 |
| ▸ | GUSB | P08236 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1560756 | 0.89 | CYP19A1 (0.77) | CYP19A1CYP1B1MEN1LMNASHBG | |
| SCHEMBL8532535 | 0.88 | CYP19A1 (0.75) | CYP19A1CYP1B1MEN1LMNASHBG | |
| SCHEMBL4243919 | 0.88 | CYP19A1 (0.75) | CYP19A1CYP1B1MEN1LMNASHBG | |
| SCHEMBL8639067 | 0.88 | CYP19A1 (0.75) | CYP19A1CYP1B1MEN1LMNASHBG | |
| SCHEMBL11531541 | 0.88 | CYP19A1 (1.00) | CYP19A1 | |
| SCHEMBL11531546 | 0.88 | CYP19A1 (1.00) | CYP19A1 | |
| SCHEMBL10605205 | 0.87 | CYP19A1 (0.73) | CYP19A1CYP1B1MEN1LMNASHBG | |
| SCHEMBL13173443 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP1B1MEN1LMNASHBG | |
| SCHEMBL1552217 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP1B1MEN1LMNASHBG | |
| SCHEMBL18784972 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP1B1MEN1LMNASHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115558695-A | Enzymatic preparation method of 3 beta-hydroxy-androst-5-ene-17-one | 上海格苓凯生物科技有限公司 | 2023-01-03 | — | — | CN | claimed |
| CN-112852767-B | Carbonyl reductase mutant and application thereof in catalytic synthesis of 17 beta-hydroxy steroid compound | 中国科学院天津工业生物技术研究所 | 2022-04-05 | — | — | CN | claimed |
| EP-2999708-A2 | PROCESSES FOR THE PREPARATION OF DEHYDROEPIANDROSTERONE AND ITS INTERMEDIATES | Dr. Reddy's Laboratories Ltd. (IN) | 2016-03-30 | — | — | EP | claimed |
| WO-2014108808-A2 | PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF TRAUMA-INDUCED NEUROPATHOLOGY AND NEURODEGENERATION | HENRY JAMES LORNE (CA) | 2014-07-17 | — | — | WO | claimed |
| EP-1420769-A2 | LIPID PROFILE MODULATION WITH STEROIDS | THE UNIVERSITY OF EDINBURGH (GB) | 2004-05-26 | — | — | EP | claimed |
| WO-2002076435-A2 | LIPID PROFILE MODULATION WITH STEROIDS | THE UNIVERSITY OF EDINBURGH (GB) | 2002-10-03 | — | — | WO | claimed |
| EP-0721461-A1 | SYNTHESIS OF 17-(3-PYRIDYL) STEROIDS | BTG INTERNATIONAL LIMITED (GB) | 1996-07-17 | — | — | EP | claimed |
| WO-1995009178-A1 | SYNTHESIS OF 17-(3-PYRIDYL) STEROIDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-04-06 | — | — | WO | claimed |
| JP-63267722-A | — | — | None | — | — | JP | disclosed |
| CN-115558695-A | Enzymatic preparation method of 3 beta-hydroxy-androst-5-ene-17-one | 上海格苓凯生物科技有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-109310727-B | Conditionally active heterodimeric polypeptides and methods of use thereof | 加利福尼亚大学董事会 | 2022-09-27 | — | — | CN | disclosed |
| CN-112852767-B | Carbonyl reductase mutant and application thereof in catalytic synthesis of 17 beta-hydroxy steroid compound | 中国科学院天津工业生物技术研究所 | 2022-04-05 | — | — | CN | disclosed |
| EP-2999708-A2 | PROCESSES FOR THE PREPARATION OF DEHYDROEPIANDROSTERONE AND ITS INTERMEDIATES | Dr. Reddy's Laboratories Ltd. (IN) | 2016-03-30 | — | — | EP | disclosed |
| WO-2014108808-A2 | PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF TRAUMA-INDUCED NEUROPATHOLOGY AND NEURODEGENERATION | HENRY JAMES LORNE (CA) | 2014-07-17 | — | — | WO | disclosed |
| EP-0133995-B1 | STEROIDS AND THERAPEUTIC COMPOSITIONS CONTAINING SAME | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-04-15 | — | — | EP | disclosed |
| EP-0423842-A2 | Steroids and therapeutic compositions containing same | Research Corporation (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4898694-A | 17-Hydroxy-steroids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1990-02-06 | — | — | US | disclosed |
| JP-S63267722-A | ANTI-OBESITY AGENT | DAIICHI YAKUHIN SANGYO KK | 1988-11-04 | — | — | JP | disclosed |
| EP-0246650-A1 | Steroids useful as anti-cancer and anti-obesity agents, a therapeutic composition containing them and use thereof for the preparation of a therapeutic composition | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1987-11-25 | — | — | EP | disclosed |
| EP-0133995-A2 | Steroids and therapeutic compositions containing same | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1985-03-13 | — | — | EP | disclosed |