Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.74 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | SHBG | P04278 | 1/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5479309 | 1.00 | CYP19A1 (0.74) | CYP19A1CYP1B1ESR1SHBGSERPINA6 | |
| SCHEMBL9938719 | 1.00 | CYP19A1 (0.74) | CYP19A1CYP1B1ESR1SHBGSERPINA6 | |
| SCHEMBL5697554 | 0.85 | CYP19A1 (1.00) | CYP19A1ESR1SHBGSERPINA6AR | |
| SCHEMBL5311348 | 0.85 | CYP19A1 (1.00) | CYP19A1ESR1SHBGSERPINA6AR | |
| SCHEMBL1418753 | 0.85 | CYP19A1 (0.73) | CYP19A1CYP1B1ESR1SHBGSERPINA6 | |
| SCHEMBL5493314 | 0.85 | CYP19A1 (0.73) | CYP19A1CYP1B1ESR1SHBGSERPINA6 | |
| SCHEMBL5574098 | 0.85 | CYP19A1 (0.73) | CYP19A1CYP1B1ESR1SHBGSERPINA6 | |
| SCHEMBL7070071 | 0.85 | CYP19A1 (1.00) | CYP19A1ESR1SHBGSERPINA6AR | |
| SCHEMBL5499393 | 0.85 | CYP19A1 (0.77) | CYP19A1CYP1B1ESR1SHBGSERPINA6 | |
| SCHEMBL606838 | 0.83 | CYP19A1 (0.70) | CYP19A1CYP1B1ESR1SHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2012773-A2 | DRUGS AND USES | Hollis-Eden Pharmaceuticals Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008039566-A2 | DRUGS AND USES | HOLLIS-EDEN PHARMACEUTICALS, INC. (US) | 2008-04-03 | — | — | WO | disclosed |