SCHEMBL4448280

SCHEMBL4448280

CCCCCCCCCC=CC=CC=Cc1cccc(O)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 3/20 0.43
F3 P13726 3/20 0.43
MMP2 P08253 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALOX15 P16050 1/20 0.43
ECE1 P42892 1/20 0.43
SGMS1 Q86VZ5 1/20 0.43
SGMS2 Q8NHU3 1/20 0.43
MUS81 Q96NY9 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SAE1 Q9UBE0 1/20 0.43
BID P55957 3/20 0.40
BCL2L1 Q07817 3/20 0.40
MCL1 Q07820 3/20 0.40
BAK1 Q16611 3/20 0.40
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
IAPP P10997 1/20 0.39
FASN P49327 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11150486 0.88 F7 (0.47) F7F3MMP2MAPTKDM4E
SCHEMBL4460164 0.88 F7 (0.47) F7F3MMP2MAPTKDM4E
SCHEMBL11043454 0.87 IAPP (0.52) F7F3MMP2MAPTKDM4E
SCHEMBL19858999 0.87 CDK4 (0.45) F7F3MMP2MAPTKDM4E
SCHEMBL4451953 0.87 CDK4 (0.45) F7F3MMP2MAPTKDM4E
SCHEMBL30735606 0.86 IAPP (0.54) F7F3MMP2MAPTKDM4E
SCHEMBL16974813 0.85 CDK4 (0.46) F7F3MMP2MAPTKDM4E
SCHEMBL20718967 0.85 CDK4 (0.46) F7F3MMP2MAPTKDM4E
SCHEMBL30331282 0.85 CDK4 (0.46) F7F3MMP2MAPTKDM4E
SCHEMBL3417309 0.85 CDK4 (0.46) F7F3MMP2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090032162-A1 BELT ASSEMBLIES AND PNEUMATIC TIRES INCLUDING THE SAME BRIDGESTONE CORPORATION (JP) 2009-02-05 US claimed
US-20090032162-A1 BELT ASSEMBLIES AND PNEUMATIC TIRES INCLUDING THE SAME BRIDGESTONE CORPORATION (JP) 2009-02-05 US disclosed