SCHEMBL4448452

SCHEMBL4448452

CCCCCCCCCCC#COCCO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
MAPT P10636 2/20 0.45
THRB P10828 1/20 0.45
HTT P42858 1/20 0.45
PTPN7 P35236 5/20 0.41
HMGCR P04035 3/20 0.41
LMNA P02545 2/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 1/20 0.41
SELP P16109 1/20 0.39
RECQL P46063 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 1/20 0.35
USP2 O75604 1/20 0.35
POLB P06746 1/20 0.35
HPGD P15428 1/20 0.35
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11849948 1.00 MEN1 (0.45) MEN1KMT2AMAPTTHRBHTT
SCHEMBL11475049 0.85 PTPN7 (0.41) MEN1KMT2AMAPTTHRBHTT
SCHEMBL10972886 0.85 PTPN7 (0.41) MEN1KMT2AMAPTTHRBPTPN7
SCHEMBL3032195 0.85 PTPN7 (0.41) MEN1KMT2AMAPTTHRBHTT
SCHEMBL11472202 0.85 PTPN7 (0.41) MEN1KMT2AMAPTTHRBHTT
SCHEMBL8000469 0.80 PTPN7 (0.37) MEN1KMT2AMAPTTHRBPTPN7
SCHEMBL7998475 0.80 PTPN7 (0.37) MEN1KMT2AMAPTTHRBPTPN7
SCHEMBL8000605 0.80 PTPN7 (0.37) MEN1KMT2AMAPTTHRBPTPN7
SCHEMBL8000478 0.80 PTPN7 (0.37) MEN1KMT2AMAPTTHRBPTPN7
SCHEMBL8003890 0.80 PTPN7 (0.37) MEN1KMT2AMAPTTHRBPTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7531334-B2 Polymeric microcarriers for cell culture functions XEROX CORPORATION (US) 2009-05-12 US disclosed
US-20070243607-A1 POLYMERIC MICROCARRIERS FOR CELL CULTURE FUNCTIONS XEROX CORPORATION (US) 2007-10-18 US disclosed
US-7276254-B2 Emulsion/aggregation polymeric microspheres for biomedical applications and methods of making same XEROX CORPORATION (US) 2007-10-02 US disclosed
EP-1640810-A1 Emulsion aggregation toner containing pigment having a small particle size Xerox Corporation (US) 2006-03-29 EP disclosed
US-20060063084-A1 Emulsion aggregation toner containing pigment having a small particle size XEROX CORPORATION (US) 2006-03-23 US disclosed
US-20030211035-A1 Emulsion/aggregation polymeric microspheres for biomedical applications and methods of making same XEROX CORPORATION 2003-11-13 US disclosed
EP-0647886-B1 Polyesteramide-siloxane toner and developer compositions XEROX CORP (US) 2000-02-23 EP disclosed
US-5486444-A Polyester processes for the preparation of toner XEROX CORPORATION (US) 1996-01-23 US disclosed
US-5466554-A Toner compositions with modified polyester resins XEROX CORPORATION (US) 1995-11-14 US disclosed
EP-0647886-A1 Polyesteramide-siloxane toner and developer compositions XEROX CORPORATION (US) 1995-04-12 EP disclosed
US-5401601-A Polyesteramide-siloxane toner and developer compositions XEROX CORPORATION (US) 1995-03-28 US disclosed
US-5391452-A Polyester toner and developer compositions XEROX CORPORATION (US) 1995-02-21 US disclosed
US-5348832-A Toner compositions XEROX CORPORATION (US) 1994-09-20 US disclosed