Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 17/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799305 | 1.00 | PDE4A (0.57) | PDE4APDE4DPDE4BPDE4CBCHE | |
| SCHEMBL2799239 | 1.00 | PDE4A (0.57) | PDE4APDE4DPDE4BPDE4CBCHE | |
| SCHEMBL2801940 | 0.90 | PDE4D (0.61) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL2798678 | 0.90 | PDE4D (0.61) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL4442028 | 0.90 | PDE4D (0.61) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL2800190 | 0.89 | PDE4A (0.54) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL2800202 | 0.87 | PDE4D (0.54) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL2798274 | 0.87 | PDE4D (0.54) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL4449911 | 0.87 | PDE4D (0.54) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL2797304 | 0.85 | PDE4D (0.74) | PDE4APDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137150-A1 | PIPERIDINONES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008110794-A1 | PIPERIDINONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2008-09-18 | — | — | WO | disclosed |