Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747321 | 0.85 | S1PR5 (0.54) | S1PR5ERN1LMNAHTTMAPK1 | |
| SCHEMBL3212416 | 0.84 | SLC2A1 (0.46) | S1PR5ERN1KMT2AMEN1ATM | |
| SCHEMBL3204784 | 0.83 | CYP19A1 (0.44) | KMT2AMEN1ATMMAPK1SMN1; SMN2 | |
| SCHEMBL3212402 | 0.81 | BRD4 (0.48) | S1PR5KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL3204885 | 0.81 | MRGPRX4 (0.43) | KMT2AMEN1ATMMAPK1SMN1; SMN2 | |
| SCHEMBL3196894 | 0.81 | SCN9A (0.44) | S1PR5KMT2AMEN1ATMMAPK1 | |
| SCHEMBL3188243 | 0.81 | MAPT (0.55) | KMT2AMEN1MAPK1ALDH1A1MAPT | |
| SCHEMBL10826146 | 0.80 | SLC2A1 (0.54) | KMT2AMEN1ATMLMNAHTT | |
| SCHEMBL3214764 | 0.80 | PTPN1 (0.42) | S1PR5LMNAHTTMAPK1SMN1; SMN2 | |
| SCHEMBL18331478 | 0.79 | MRGPRX4 (0.47) | S1PR5ERN1KMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010495-A2 | NEW HYDROXYPHENYL DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | Mutabilis SA (FR) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007135562-A2 | HYDROXYPHENYL DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS S.A. (FR) | 2007-11-29 | — | — | WO | disclosed |