Acetic Acid

Acetic Acid

SCHEMBL4449014

CC(=O)O.CC(=O)O.CC(=O)O.[P]

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.88
LCK P06239 1/20 0.88
FYN P06241 1/20 0.88
LMNA P02545 3/20 0.56
TSHR P16473 3/20 0.50
THPO P40225 1/20 0.50
CA1 P00915 3/20 0.46
ALOX15 P16050 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
CA2 P00918 2/20 0.44
CA9 Q16790 1/20 0.44
ALDH1A1 P00352 5/20 0.39
TP53 P04637 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 1/20 0.39
PTGS1 P23219 1/20 0.39
MMP12 P39900 1/20 0.39
CA4 P22748 1/20 0.39
SLC15A2 Q16348 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL4449019 1.00
Acetic Acid SCHEMBL30447559 0.94
Acetic Acid SCHEMBL1331719 0.94
Acetic Acid SCHEMBL1331810 0.94
Acetic Acid SCHEMBL1330415 0.94
Acetic Acid SCHEMBL7472549 0.94
Acetic Acid SCHEMBL11142541 0.94 FFAR3 (1.00) FFAR3LCKFYNLMNATSHR
Acetic Acid SCHEMBL8742314 0.94 FFAR3 (1.00) FFAR3LCKFYNLMNATSHR
Acetic Acid SCHEMBL6788 0.94 FFAR3 (1.00) FFAR3LCKFYNLMNATSHR
Acetic Acid SCHEMBL41073 0.94 FFAR3 (1.00) FFAR3LCKFYNLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0835901-A2 A method for preparation of recycled polyols and a method for manufacturing polyurethane foams SAMSUNG ELECTRONICS CO., LTD. (KR) 1998-04-15 EP claimed
CN-118139918-A Method for cleaving (poly) urethanes 科思创德国股份有限公司 2024-06-04 CN disclosed
WO-2009065203-A2 EFFLUENTS TREATMENT NATURAL SYSTEM SANTANA DE LIMAS GALDINO (BR) 2009-05-28 WO disclosed
EP-0953418-B1 Method for decomposition treating article having cured thermosetting resin MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2005-12-28 EP disclosed
EP-0835901-A2 A method for preparation of recycled polyols and a method for manufacturing polyurethane foams SAMSUNG ELECTRONICS CO., LTD. (KR) 1998-04-15 EP disclosed
US-4454312-A CONTAINING ZIRCONIUM TOYO BOSEKI KABUSHIKI KAISHA (JP) 1984-06-12 US disclosed