SCHEMBL4449119

SCHEMBL4449119

[Li]C(C)=CC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6699789 1.00
SCHEMBL16178515 0.74
SCHEMBL18943635 0.74 TSHR (0.30)
SCHEMBL22212 0.74
SCHEMBL22211 0.74
SCHEMBL11330170 0.71
SCHEMBL11330164 0.71
SCHEMBL6724394 0.70
SCHEMBL938159 0.70
SCHEMBL25009038 0.67 TSHR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5329056-A Preparation of substituted cyclopentadienes ALBEMARLE CORPORATION (US) 1994-07-12 US claimed
CN-101151234-B Process for producing cyclopropylphenol derivative SANKYO AGRO CO LTD 2011-06-15 CN disclosed
US-7629494-B2 Process for producing cyclopropylphenol derivative MITSUI CHEMICALS AGRO, INC. (JP) 2009-12-08 US disclosed
US-20090054681-A1 Production Process of cyclopropylphenol derivatives SANKYO AGRO COMPANY, LIMITED (JP) 2009-02-26 US disclosed
CN-101151234-A Process for producing cyclopropylphenol derivative SANKYO AGRO CO LTD (JP) 2008-03-26 CN disclosed
EP-1880987-A1 PROCESS FOR PRODUCING CYCLOPROPYLPHENOL DERIVATIVE Sankyo Agro Company, Limited (JP) 2008-01-23 EP disclosed
US-6831096-B2 Effective against both A and B forms of influenza; oral bioavailability ABBOTT LABORATORIES 2004-12-14 US disclosed
US-20040097471-A1 Inhibitors of neuraminidases ABBVIE INC. 2004-05-20 US disclosed
US-6455571-B1 ESPECIALLY, INFLUENZA NEURAMINIDASE. ABBOTT LABORATORIES 2002-09-24 US disclosed
EP-0525782-A1 Process for the preparation of functionalised diphenylsiloxane-dimethylsiloxane copolymers Dow Corning Toray Silicone Company, Limited (JP) 1993-02-03 EP disclosed