SCHEMBL44493

SCHEMBL44493

C1=Cc2ccccc2SC1

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3643757 1.00 MEN1 (0.30) MEN1ALDH1A1GAAKMT2ATRPA1
SCHEMBL29569587 1.00 MEN1 (0.30) MEN1ALDH1A1GAAKMT2ATRPA1
SCHEMBL28910128 0.91
Acetic Acid SCHEMBL9788861 0.86 NOTUM (0.37) MEN1KMT2A
SCHEMBL10463884 0.82 HPGD (0.35) MEN1ALDH1A1KMT2A
SCHEMBL3094885 0.82 HTR2C (0.53)
SCHEMBL7619455 0.82 GAA (0.36) MEN1ALDH1A1GAAKMT2A
SCHEMBL7916390 0.82 CYP2B6 (0.35)
Benzothiophene SCHEMBL29032817 0.80
SCHEMBL6200557 0.79 MEN1 (0.35) MEN1ALDH1A1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4126 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595275-B2 Fluorine-containing compound and anti-cancer medical use thereof ASCENTAWITS PHARMACEUTICALS, LTD. (CN) 2026-04-07 US claimed
US-20260048156-A1 FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS Atoms for Cure GmbH (DE) 2026-02-19 US claimed
EP-4658713-A1 METHOD FOR DEGRADING AND RECYCLING A POLYURETHANE AND THE DEGRADATION PRODUCT THEREOF Covestro Deutschland AG (DE) 2025-12-10 EP claimed
EP-3971194-B1 FLUORINE-CONTAINING COMPOUND AND ANTI-CANCER MEDICAL USE THEREOF ASCENTAWITS PHARMACEUTICALS LTD (CN) 2025-12-03 EP claimed
US-20250302831-A1 THERAPY FOR ALCOHOL-RELATED LIVER DISEASE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, OFFICE OF THE GENERAL COUNSEL (024) 2025-10-02 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
EP-4486395-A1 PRECURSOR MARKERS AND RADIOTRACERS WITH THREE OR MORE TARGETING VECTORS FOR THERANOSTICS USED IN NUCLEAR MEDICINE Atoms for Cure GmbH (DE) 2025-01-08 EP claimed
EP-4452326-A1 FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS Atoms for Cure GmbH (DE) 2024-10-30 EP claimed
CN-118834240-A Fluorine-containing compound and anticancer medical application 深圳艾欣达伟医药科技有限公司 2024-10-25 CN claimed
CN-118785925-A Marker precursors and radiotracers with three or more targeting vectors for use in diagnostic nuclear medicine therapies 原子治疗有限公司 2024-10-15 CN claimed
US-4857431-A Photoconductive composition FUJI PHOTO FILM CO., LTD. (JP) 1989-08-15 US claimed
EP-0271550-A1 BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM ALKALOIDA VEGYéSZETI GYáR (HU) 1988-06-22 EP claimed
EP-0264198-A2 Optical information recording medium CANON KABUSHIKI KAISHA (JP) 1988-04-20 EP claimed
WO-1988000197-A1 BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM ALKALOIDA VEGYE^´SZETI GYA^´R (HU) 1988-01-14 WO claimed
EP-0079683-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-06 EP claimed
CN-86103229-A The preparation method of 2-thiochromene fork acetylacetic ester 1986-11-19 CN claimed
US-4548886-A ELECTROGRAPHIC FILMS; OPTICAL RECORDING MEDIA CANON KABUSHIKI KAISHA (JP) 1985-10-22 US claimed
US-4421837-A Method of improving image sharpness of an electrophotographic photosensitive plate MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1983-12-20 US claimed
US-4318981-A Homogeneous specific binding assay employing an intramolecularly modulated photogenic enzyme substrate label MILES LABORATORIES, INC. (US) 1982-03-09 US claimed
US-4221806-A ANTIALLERGENS CIBA-GEIGY CORPORATION (US) 1980-09-09 US claimed