Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | PDE8B | O95263 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452843 | 0.94 | — | — | |
| SCHEMBL12089502 | 0.83 | PDE8B (0.36) | PDE8BUSP2SMN1; SMN2TP53HPGD | |
| SCHEMBL12090067 | 0.83 | PDE8B (0.36) | PDE8BUSP2SMN1; SMN2TP53HPGD | |
| SCHEMBL8860611 | 0.83 | PDE8B (0.36) | PDE8BUSP2SMN1; SMN2TP53HPGD | |
| SCHEMBL797696 | 0.81 | PDE8B (0.35) | PDE8BUSP2SMN1; SMN2TP53HPGD | |
| SCHEMBL13502926 | 0.80 | ANPEP (0.34) | ANPEPPDE8BUSP2SMN1; SMN2TP53 | |
| SCHEMBL4372558 | 0.80 | PDE8B (0.36) | ANPEPPDE8BUSP2SMN1; SMN2TP53 | |
| SCHEMBL23501590 | 0.79 | USP2 (0.37) | USP2SMN1; SMN2TP53HPGDALOX12 | |
| SCHEMBL8861118 | 0.79 | USP2 (0.33) | PDE8BUSP2SMN1; SMN2TP53HPGD | |
| SCHEMBL24435070 | 0.79 | USP2 (0.33) | PDE8BUSP2SMN1; SMN2TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819000-B1 | NODULISPORIC ACID DERIVATIVES | MERCK & CO INC (US) | 2009-07-08 | — | — | EP | disclosed |
| EP-0819000-A4 | NODULISPORIC ACID DERIVATIVES | MERCK & CO INC (US) | 2001-04-11 | — | — | EP | disclosed |
| US-5962499-A | ACARICIDAL, ANTIPARASITIC, INSECTICIDAL AND ANTHELMINTIC AGENTS | MERCK & CO., INC. (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0819000-A1 | NODULISPORIC ACID DERIVATIVES | Merck & Co., Inc. (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996029073-A1 | NODULISPORIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1996-09-26 | — | — | WO | disclosed |