Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3299205 | 1.00 | MAPT (0.52) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL3299208 | 1.00 | MAPT (0.52) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL3301699 | 0.93 | MAPT (0.53) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL3301703 | 0.93 | MAPT (0.53) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL3303528 | 0.89 | MAPT (0.51) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL3303525 | 0.89 | MAPT (0.51) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL3299740 | 0.87 | MAPT (0.51) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL3299058 | 0.87 | MAPT (0.51) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL3299054 | 0.87 | MAPT (0.51) | MAPTMEN1KMT2ATP53GAA | |
| SCHEMBL3299739 | 0.87 | MAPT (0.51) | MAPTMEN1KMT2ATP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120911-A1 | AMIDE AND UREA DERIVATIVES FOR THE TREATMENT OF METABOLIC DISEASES | Prosidion Limited (GB) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008099221-A1 | AMIDE AND UREA DERIVATIVES FOR THE TREATMENT OF METABOLIC DISEASES | PROSIDION LIMITED (GB) | 2008-08-21 | — | — | WO | disclosed |